Singer P A, Mehler S
Research Service, Kansas City Veterans Affairs Medical Center, Missouri 64128.
Exp Neurol. 1990 Apr;108(1):86-7. doi: 10.1016/0014-4886(90)90012-h.
We used [2-14C]deoxyglucose as a marker of increased metabolism of the hypoglossal nucleus after transection of its nerve. We studied this metabolism in 3-, 12-, and 24-month-old rats. We found an increase in glucose uptake in the control nucleus of 24-month-old rats which was significant when compared to that of 3-month-old rats. We also found a twofold increase in the difference between glucose uptake on the side of nerve transection compared to the control side in old rats.
我们使用[2-¹⁴C]脱氧葡萄糖作为舌下神经横断后舌下神经核代谢增加的标志物。我们在3个月、12个月和24个月大的大鼠中研究了这种代谢情况。我们发现，与3个月大的大鼠相比，24个月大的大鼠对照核中的葡萄糖摄取量增加，且差异显著。我们还发现，老年大鼠神经横断侧与对照侧的葡萄糖摄取差异增加了两倍。
