Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI 48202, USA.
Eur Urol. 2013 Mar;63(3):573-8. doi: 10.1016/j.eururo.2012.11.029. Epub 2012 Nov 19.
We describe a reproducible technique for achieving cold ischemia with intraoperative tumor assessment during robotic partial nephrectomy (RPN) that recapitulates the open approach: intracorporeal cooling and extraction (ICE). A total of seven patients underwent the ICE modification of RPN by transperitoneal (n=5) and retroperitoneal (n=2) approaches. A Gelpoint access port was used for the camera and assistant ports. Following hilar clamping, ice slush was introduced through the Gelpoint via syringes and applied over the kidney surface. The excised tumor was immediately extracted through the Gelpoint, allowing gross margin assessment by pathology during the renorrhaphy. RPN was achieved in all cases with successful introduction of ice slush and tumor extraction while on clamp. Median RENAL nephrometry score was 8 (range: 6-10), and there was one solitary kidney. Mean cold ischemia time was 19.6 min (range: 8-37) and mean estimated blood loss was 296.4 ml (range: 50-1000). Renal parenchymal temperatures <16°C were achieved within 7 min of cold ischemia and there was no drop in core body temperature >0.5°C during any procedures. Intraoperative assessment of the excised tumor showed adequate gross margins in all cases and final pathology confirmed negative surgical margins.
我们描述了一种可重现的技术,可在机器人辅助部分肾切除术(RPN)期间实现冷缺血,并在术中评估肿瘤,该技术模拟了开放性手术:经腹腔(n=5)和腹膜后(n=2)入路进行的腔内冷却和提取(ICE)。共有 7 名患者接受了经腹腔和腹膜后入路的 ICE 改良 RPN。Gelpoint 操作端口用于摄像头和助手端口。在肾门夹闭后,通过注射器将冰泥注入 Gelpoint 并涂在肾脏表面。切除的肿瘤立即通过 Gelpoint 提取,从而在肾缝合过程中由病理科进行大体切缘评估。所有病例均成功实施了 ICE 改良 RPN,并在夹闭时成功引入冰泥和提取肿瘤。中位 RENAL 肾部分切除术评分 8 分(范围:6-10 分),且有 1 例为单肾。冷缺血时间的中位数为 19.6 分钟(范围:8-37 分钟),估计失血量的中位数为 296.4 毫升(范围:50-1000 毫升)。冷缺血 7 分钟内可达到肾实质温度<16°C,且在任何手术过程中核心体温均未下降>0.5°C。术中对切除的肿瘤进行评估,所有病例均显示出足够的大体切缘,最终的病理检查证实无外科切缘阳性。