Department of Surgery, Morioka Municipal Hospital, Motomiya, Morioka, Japan.
Diagn Pathol. 2012 Nov 27;7:162. doi: 10.1186/1746-1596-7-162.
Nipple adenoma is a relatively rare benign breast neoplasm, and cases of the disease arising from the axillary accessory breast have very seldom been reported in the English literature. We report a case of nipple adenoma arising from axillary accessory breast including clinical and pathological findings. An 82-year-old woman presented with the complaint of a small painful mass in the right axilla. Physical examination confirmed a well-defined eczematous crusted mass that was 8 mm in size. The diagnosis of nipple adenoma was made from an excisional specimen on the basis of characteristic histological findings. Microscopic structural features included a compact proliferation of small tubules lined by epithelial and myoepithelial cells, and the merging of glandular epithelial cells of the adenoma into squamous epithelial cells in the superficial epidermal layer. Because clinically nipple adenoma may resemble Paget's disease and pathologically can be misinterpreted as tubular carcinoma, the correct identification of nipple adenoma is an important factor in the differential diagnosis for axillary tumor neoplasms.
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乳头腺瘤是一种相对罕见的良性乳腺肿瘤,英文文献中很少有报道腋窝副乳腺发生该病的病例。我们报告一例腋窝副乳腺发生的乳头腺瘤,包括临床和病理发现。一名 82 岁女性因右腋窝出现小而疼痛的肿块就诊。体格检查证实为大小为 8 毫米的边界清楚的湿疹性结痂肿块。根据特征性组织学发现,从切除标本中诊断为乳头腺瘤。微观结构特征包括小的管状上皮和肌上皮细胞的致密增生,并且腺瘤的腺上皮细胞融合到表皮浅层的鳞状上皮细胞中。因为临床上乳头腺瘤可能类似于派杰氏病,病理上可能被误诊为管状癌,因此正确识别乳头腺瘤是腋窝肿瘤性病变鉴别诊断的重要因素。