Fitzgerald Tove L, Durrheim David N, Merritt Tony D, Birch Christopher, Tran Thomas
CNC Health Protection, Hunter New England Population Health, Wallsend, New South Wales, Australia.
Commun Dis Intell Q Rep. 2012 Sep 30;36(3):E277-80. doi: 10.33321/cdi.2012.36.22.
Measles virus (MV) eradication is biologically, technically and operationally feasible. An essential feature in understanding the chain of MV transmission is its incubation period, that is, the time from infection to the onset of symptoms. This period is important for determining the likely source of infection and directing public health measures to interrupt ongoing transmission. Long measles incubation periods have rarely been documented in the literature. We report on a previously healthy 11-year-old Australian boy who was confirmed with measles genotype D9 infection following travel in the Philippines. Epidemiological evidence supported an unusually long incubation period of at least 23 days and virological evidence was consistent with this finding. Although public health control measures such as post exposure prophylaxis, isolation and surveillance of susceptible individuals should continue to be based on the more common incubation period, a longer incubation period may occasionally explain an unexpected measles case.
消灭麻疹病毒在生物学、技术和操作上都是可行的。理解麻疹病毒传播链的一个关键特征是其潜伏期,即从感染到症状出现的时间。这段时间对于确定可能的感染源以及指导公共卫生措施以中断正在进行的传播至关重要。文献中很少记录到麻疹的长潜伏期。我们报告了一名此前健康的11岁澳大利亚男孩,他在菲律宾旅行后被确诊感染麻疹基因型D9。流行病学证据支持至少23天的异常长潜伏期,病毒学证据也与这一发现一致。尽管诸如暴露后预防、易感个体的隔离和监测等公共卫生控制措施应继续基于更常见的潜伏期,但较长的潜伏期偶尔可能解释意外的麻疹病例。