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住院医师维生素 D 缺乏及其与代谢指标的关系。

Vitamin D deficiency among medical residents and its relationship with metabolic indices.

机构信息

Endocrinology Service, Experimental Endocrinology Unit, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social 11560 Mexico City, Mexico.

出版信息

Endocr Pract. 2013 Jan-Feb;19(1):59-63. doi: 10.4158/EP12185.OR.

Abstract

OBJECTIVE

To evaluate different elements of the calciotropic system in a group of house staff physicians, comparing them with age, gender, and body mass index (BMI) matched controls.

METHODS

We measured vitamin D, calcium, phosphorus, parathyroid hormone (PTH), glucose, insulin (estimating the insulin resistance index by the homeostatic model [HOMA]), and lipid levels in 20 medical residents and 20 age-, gender-, and BMI-matched controls. We looked for correlations between elements of the calciotropic system and metabolic indices.

RESULTS

Medical residents and controls were similar in regard to gender distribution, weight, height, BMI, abdominal circumference, as well as systolic and diastolic blood pressure. No differences were found between the two groups in regard to low-density lipoprotein (LDL)-cholesterol, high-density lipoprotein (HDL)-cholesterol, plasma insulin levels, and HOMA-IR. Vitamin D and calcium levels were significantly lower among the medical residents (P = .001 and P = .003, respectively), whereas PTH concentrations tended to be higher. We found an inverse correlation between triglyceride concentrations and vitamin D (r = -0.31, P = .04).

CONCLUSION

Vitamin D deficiency among resident physicians is frequent and could have metabolic effects. Our findings highlight the consequences of the lack of sun exposure due to occupational reasons. We recommend a higher intake of vitamin D during this period.

摘要

目的

评估一组住院医师中钙调节系统的不同元素,并与年龄、性别和体重指数(BMI)匹配的对照组进行比较。

方法

我们测量了 20 名住院医师和 20 名年龄、性别和 BMI 匹配的对照组的维生素 D、钙、磷、甲状旁腺激素(PTH)、血糖、胰岛素(通过稳态模型评估胰岛素抵抗指数[HOMA])和血脂水平。我们寻找钙调节系统元素与代谢指数之间的相关性。

结果

住院医师和对照组在性别分布、体重、身高、BMI、腰围以及收缩压和舒张压方面相似。两组在低密度脂蛋白(LDL)-胆固醇、高密度脂蛋白(HDL)-胆固醇、血浆胰岛素水平和 HOMA-IR 方面无差异。住院医师的维生素 D 和钙水平明显较低(P =.001 和 P =.003),而 PTH 浓度趋于升高。我们发现甘油三酯浓度与维生素 D 呈负相关(r = -0.31,P =.04)。

结论

住院医师中维生素 D 缺乏很常见,可能会产生代谢影响。我们的发现强调了由于职业原因缺乏阳光照射的后果。我们建议在此期间增加维生素 D 的摄入量。

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