Department of Surgery K, University of Copenhagen, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark.
World J Surg. 2013 Feb;37(2):306-11. doi: 10.1007/s00268-012-1842-3.
A systemically altered connective tissue metabolism has been demonstrated in patients with abdominal wall hernias. The most pronounced connective tissue changes are found in patients with direct or recurrent inguinal hernias as opposed to patients with indirect inguinal hernias. The aim of the present study was to assess whether direct or recurrent inguinal hernias are associated with an elevated rate of ventral hernia surgery.
In the nationwide Danish Hernia Database, a cohort of 92,457 patients operated on for inguinal hernias was recorded from January 1998 until June 2010. Eight-hundred forty-three (0.91 %) of these patients underwent a ventral hernia operation between January 2007 and June 2010. A multivariate logistic regression analysis was applied to assess an association between inguinal and ventral hernia repair.
Direct (Odds Ratio [OR] = 1.28 [95 % CI, 1.08-1.51]) and recurrent (OR = 1.76, [95 % CI, 1.39-2.23]) inguinal hernias were significantly associated with ventral hernia repair after adjustment for age, gender, and surgical approach (open or laparoscopic).
Patients with direct and recurrent inguinal herniation are more prone to ventral hernia repair than patients with indirect inguinal herniation. This is the first study to show that herniogenesis is associated with type of inguinal hernia.
已在腹壁疝患者中证实存在系统性结缔组织代谢改变。在直接或复发性腹股沟疝患者中发现最明显的结缔组织变化，而在间接腹股沟疝患者中则没有。本研究的目的是评估直接或复发性腹股沟疝是否与较高的腹疝手术率相关。
在全国丹麦疝数据库中，记录了 1998 年 1 月至 2010 年 6 月期间因腹股沟疝接受手术的 92457 例患者。其中 843 例（0.91%）在 2007 年 1 月至 2010 年 6 月期间接受了腹疝手术。采用多变量逻辑回归分析评估腹股沟疝和腹疝修复之间的关联。
直接（比值比[OR] = 1.28 [95%置信区间，1.08-1.51]）和复发性（OR = 1.76，[95%置信区间，1.39-2.23]）腹股沟疝在调整年龄、性别和手术方法（开放或腹腔镜）后与腹疝修复显著相关。
直接和复发性腹股沟疝患者比间接腹股沟疝患者更容易进行腹疝修复。这是第一项表明疝发生与腹股沟疝类型相关的研究。
