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青少年特发性关节炎患儿非骨水泥型全髋关节置换术十年的结果。

The results of uncemented total hip replacement in children with juvenile idiopathic arthritis at ten years.

作者信息

Daurka J S, Malik A K, Robin D A, Witt J D

机构信息

St George's Healthcare NHS Trust, Blackshaw Road, Tooting, London SW17 0QT, UK.

出版信息

J Bone Joint Surg Br. 2012 Dec;94(12):1618-24. doi: 10.1302/0301-620X.94B12.29124.

Abstract

The inherent challenges of total hip replacement (THR) in children include the choice of implant for the often atypical anatomical morphology, its fixation to an immature growing skeleton and the bearing surface employed to achieve a successful long-term result. We report the medium-term results of 52 consecutive uncemented THRs undertaken in 35 paediatric patients with juvenile idiopathic arthritis. The mean age at the time of surgery was 14.4 years (10 to 16). The median follow-up was 10.5 years (6 to 15). During the study period 13 THRs underwent revision surgery. With revision as an endpoint, subgroup analysis revealed 100% survival of the 23 ceramic-on-ceramic THRs and 55% (16 of 29) of the metal- or ceramic-on-polyethylene. This resulted in 94% (95% CI 77.8 to 98.4) survivorship of the femoral component and 62% (95% CI 41.0 to 78.0) of the acetabular component. Revision of the acetabular component for wear and osteolysis were the most common reasons for failure accounting for 11 of the 13 revisions. The success seen in patients with a ceramic-on-ceramic articulation seems to indicate that this implant strategy has the potential to make a major difference to the long-term outcome in this difficult group of patients.

摘要

儿童全髋关节置换术(THR)面临的固有挑战包括,针对通常不典型的解剖形态选择植入物、将其固定于未成熟的生长骨骼以及采用何种承重表面以实现长期成功效果。我们报告了35例患有幼年特发性关节炎的儿科患者连续接受的52例非骨水泥型THR的中期结果。手术时的平均年龄为14.4岁(10至16岁)。中位随访时间为10.5年(6至15年)。在研究期间,13例THR接受了翻修手术。以翻修为终点进行亚组分析显示,23例陶瓷对陶瓷THR的生存率为100%,而金属对聚乙烯或陶瓷对聚乙烯的为55%(29例中的16例)。这导致股骨组件的生存率为94%(95%CI 77.8至98.4),髋臼组件的生存率为62%(95%CI 41.0至78.0)。因磨损和骨溶解而翻修髋臼组件是最常见的失败原因,在13例翻修手术中有11例为此原因。陶瓷对陶瓷关节置换患者所取得的成功似乎表明,这种植入策略有可能对这一困难患者群体的长期预后产生重大影响。

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