Van Beckhoven D, Buvé A, Ruelle J, Seyler L, Sasse A
O.D. Public Health and Surveillance, Scientific Institute of Public Health, Brussels, Belgium.
Acta Clin Belg. 2012 Sep-Oct;67(5):333-7. doi: 10.2143/ACB.67.5.2062686.
In Belgium, individual laboratory and treatment data of all HIV-infected patients seen in the 9 AIDS Reference Centres and 7 AIDS Reference Laboratories are collected prospectively since 2006. We present here an analysis of patients recorded in the cohort database between 1st of January 2006 and 31st of December 2008. During that period, 11982 patients were under medical follow-up in Belgium. Sixty-one percent of the patients were male and the median age was 39.8 at the time of first recorded viral load. Among the patients whose nationality or probable mode of transmission was recorded, nearly half (48.0%) were Belgian and 38.3% originated from Sub-Saharan Africa; heterosexual contacts were reported in the majority of cases (56.0%) followed by homosexual contacts (35.3%). A total of 145 deaths were reported. Around three quarters of the patients were on ART. The median CD4 cell count rose from 470 cells/mm3 in 2006 to 501 cells/mm3 in 2008. This cohort enabled us to obtain comprehensive information on the numbers and characteristics of HIV-infected patients currently being followed up in Belgium, and on trends in antiretroviral therapy and biological results. This will serve for planning purposes, evaluation of access to care and as a source of information for further studies.
自2006年起，比利时前瞻性收集了9个艾滋病参考中心和7个艾滋病参考实验室中所有接受治疗的HIV感染患者的个人实验室及治疗数据。在此，我们呈现了2006年1月1日至2008年12月31日期间队列数据库中记录患者的分析结果。在此期间，比利时有11982名患者接受医学随访。61%的患者为男性，首次记录病毒载量时的中位年龄为39.8岁。在记录了国籍或可能传播途径的患者中，近一半（48.0%）为比利时人，38.3%来自撒哈拉以南非洲；大多数病例（56.0%）报告为异性性接触，其次是同性性接触（35.3%）。共报告了145例死亡。约四分之三的患者接受抗逆转录病毒治疗。CD4细胞计数中位数从2006年的470个细胞/mm³升至2008年的501个细胞/mm³。该队列使我们能够获取有关比利时目前接受随访的HIV感染患者的数量和特征、抗逆转录病毒治疗趋势及生物学结果的全面信息。这将用于规划目的、评估医疗服务可及性，并作为进一步研究的信息来源。
