Paediatric HIV Diagnostic Syndicate, Wits Health Consortium, Parktown, South Africa.
Pediatr Infect Dis J. 2013 May;32(5):486-8. doi: 10.1097/INF.0b013e31827b4775.
Diagnosing HIV infection in infants by p24 antigen detection at point of care is likely to reduce infant morbidity and mortality. A fourth-generation rapid test evaluated on 202 stored samples from children of known age and clinical presentation demonstrated a sensitivity of <2% for detecting p24 antigen in 61 HIV-infected infants and demonstrated 100% sensitivity and specificity for detecting HIV antibodies in infants aged 6 months and younger.
在护理点通过 p24 抗原检测诊断婴儿 HIV 感染可能会降低婴儿的发病率和死亡率。在已知年龄和临床表现的儿童的 202 个存储样本上评估的第四代快速检测显示，在 61 名 HIV 感染婴儿中检测 p24 抗原的敏感性<2%，并在 6 个月及以下婴儿中检测 HIV 抗体的敏感性和特异性为 100%。
