• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Decitabine facilitates the generation and immunosuppressive function of regulatory γδT cells derived from human peripheral blood mononuclear cells.

作者信息

Hu Y, Cui Q, Gu Y, Sheng L, Wu K, Shi J, Tan Y, Fu H, Liu L, Fu S, Yu X, Huang H

出版信息

Leukemia. 2013 Jul;27(7):1580-5. doi: 10.1038/leu.2012.345. Epub 2012 Nov 29.

DOI:10.1038/leu.2012.345
PMID:23192015
Abstract
摘要

相似文献

1
Decitabine facilitates the generation and immunosuppressive function of regulatory γδT cells derived from human peripheral blood mononuclear cells.地西他滨促进源自人外周血单个核细胞的调节性γδT细胞的生成及免疫抑制功能。
Leukemia. 2013 Jul;27(7):1580-5. doi: 10.1038/leu.2012.345. Epub 2012 Nov 29.
2
Kinetics of pDCs, mDCs, γδT cells and regulatory T cells in association with graft versus host disease after hematopoietic stem cell transplantation.造血干细胞移植后移植物抗宿主病相关的浆细胞样树突状细胞、髓样树突状细胞、γδT 细胞和调节性 T 细胞的动力学。
Int J Lab Hematol. 2011 Aug;33(4):378-90. doi: 10.1111/j.1751-553X.2011.01300.x. Epub 2011 Mar 28.
3
Simple in vitro generation of human leukocyte antigen-G-expressing T-regulatory cells through pharmacological hypomethylation for adoptive cellular immunotherapy against graft-versus-host disease.通过药物性低甲基化在体外简单生成表达人类白细胞抗原-G的调节性T细胞用于过继性细胞免疫疗法治疗移植物抗宿主病
Cytotherapy. 2017 Apr;19(4):521-530. doi: 10.1016/j.jcyt.2017.01.004. Epub 2017 Feb 2.
4
Transplantation in the onco-hematology field: focus on the manipulation of αβ and γδ T cells.肿瘤血液病学领域的移植:聚焦于αβ和γδ T 细胞的操作。
Pathol Res Pract. 2012 Feb 15;208(2):67-73. doi: 10.1016/j.prp.2011.10.006. Epub 2011 Nov 23.
5
[Effect of decitabine on immune regulation in patients with acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation].
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2014 Oct;22(5):1448-52. doi: 10.7534/j.issn.1009-2137.2014.05.050.
6
DNA methyltransferase inhibition increases efficacy of adoptive cellular immunotherapy of murine breast cancer.DNA甲基转移酶抑制增强了小鼠乳腺癌过继性细胞免疫治疗的疗效。
Cancer Immunol Immunother. 2016 Sep;65(9):1061-73. doi: 10.1007/s00262-016-1868-8. Epub 2016 Jul 14.
7
Simultaneous generation of multivirus-specific and regulatory T cells for adoptive immunotherapy.用于过继免疫治疗的多病毒特异性和调节性 T 细胞的同时生成。
J Immunother. 2012 Jan;35(1):42-53. doi: 10.1097/CJI.0b013e31823569e2.
8
Therapeutic potential of induced and natural FoxP3(+) regulatory T cells for the treatment of Graft-versus-host disease.诱导性和天然 FoxP3(+)调节性 T 细胞治疗移植物抗宿主病的治疗潜力。
Arch Immunol Ther Exp (Warsz). 2012 Jun;60(3):183-90. doi: 10.1007/s00005-012-0172-3. Epub 2012 Apr 5.
9
The graft content of donor T cells expressing gamma delta TCR+ and CD4+foxp3+ predicts the risk of acute graft versus host disease after transplantation of allogeneic peripheral blood stem cells from unrelated donors.表达γδTCR+和CD4+foxp3+的供体T细胞的移植物含量可预测无关供体异基因外周血干细胞移植后急性移植物抗宿主病的风险。
Clin Cancer Res. 2007 May 15;13(10):2916-22. doi: 10.1158/1078-0432.CCR-06-2602.
10
Interleukin-17-producing T-helper cells as new potential player mediating graft-versus-host disease in patients undergoing allogeneic stem-cell transplantation.产生白细胞介素-17的辅助性T细胞作为介导异基因干细胞移植患者移植物抗宿主病的新潜在因素。
Transplantation. 2009 Dec 15;88(11):1261-72. doi: 10.1097/TP.0b013e3181bc267e.

引用本文的文献

1
γδ T cells in hematological malignancies: mechanisms and therapeutic strategies.血液系统恶性肿瘤中的γδ T细胞:作用机制与治疗策略
Blood Sci. 2024 Dec 11;7(1):e00213. doi: 10.1097/BS9.0000000000000213. eCollection 2025 Jan.
2
Classification and function of γδT cells and its research progress in anti-glioblastoma.γδT细胞的分类、功能及其在抗胶质母细胞瘤中的研究进展
Discov Oncol. 2023 Aug 19;14(1):150. doi: 10.1007/s12672-023-00770-8.
3
Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism.通过免疫非依赖机制,用低剂量地西他滨增强化疗。
JCI Insight. 2022 Nov 22;7(22):e159419. doi: 10.1172/jci.insight.159419.
4
Regulation and Functions of Protumoral Unconventional T Cells in Solid Tumors.实体瘤中促肿瘤非常规T细胞的调控与功能
Cancers (Basel). 2021 Jul 16;13(14):3578. doi: 10.3390/cancers13143578.
5
The Roles of γδ T Cells in Hematopoietic Stem Cell Transplantation.γδ T 细胞在造血干细胞移植中的作用。
Cell Transplant. 2020 Jan-Dec;29:963689720966980. doi: 10.1177/0963689720966980.
6
Pro-tumor γδ T Cells in Human Cancer: Polarization, Mechanisms of Action, and Implications for Therapy.促肿瘤 γδ T 细胞在人类癌症中的作用:极化、作用机制及治疗意义。
Front Immunol. 2020 Sep 16;11:2186. doi: 10.3389/fimmu.2020.02186. eCollection 2020.
7
Decitabine attenuates dextran sodium sulfate‑induced ulcerative colitis through regulation of immune regulatory cells and intestinal barrier.地西他滨通过调节免疫调节细胞和肠道屏障来减轻葡聚糖硫酸钠诱导的溃疡性结肠炎。
Int J Mol Med. 2020 Aug;46(2):583-594. doi: 10.3892/ijmm.2020.4605. Epub 2020 May 18.
8
Vitamin C supports conversion of human γδ T cells into FOXP3-expressing regulatory cells by epigenetic regulation.维生素 C 通过表观遗传调控支持将人 γδ T 细胞转化为 FOXP3 表达的调节性细胞。
Sci Rep. 2020 Apr 16;10(1):6550. doi: 10.1038/s41598-020-63572-w.
9
Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer.基于全基因组 DNA 甲基化特征预测贝伐珠单抗联合新辅助化疗治疗乳腺癌的病理完全缓解。
PLoS One. 2020 Apr 16;15(4):e0230248. doi: 10.1371/journal.pone.0230248. eCollection 2020.
10
Methionine Attenuates Lipopolysaccharide-Induced Inflammatory Responses via DNA Methylation in Macrophages.蛋氨酸通过巨噬细胞中的DNA甲基化减轻脂多糖诱导的炎症反应。
ACS Omega. 2019 Jan 31;4(1):2331-2336. doi: 10.1021/acsomega.8b03571. Epub 2019 Jan 30.