Motosugi Utaroh, Yamaguchi Hiroshi, Furukawa Toru, Ichikawa Tomoaki, Hatori Takashi, Fujita Izumi, Yamamoto Masakazu, Motoi Fuyuhiko, Kanno Atsushi, Watanabe Tomoo, Koike Naoto, Koyama Isamu, Kobayashi Junya, Shimizu Michio
Department of Pathology, Saitama Medical University, International Medical Center, Hidaka, Japan.
J Comput Assist Tomogr. 2012 Nov-Dec;36(6):710-7. doi: 10.1097/RCT.0b013e31826d1fc8.
The objective of this study was to describe the imaging findings for intraductal tubulopapillary neoplasms of the pancreas.
Eleven pancreatic tumors pathologically confirmed as intraductal tubulopapillary neoplasm were retrospectively collected. The dynamic contrast-enhanced computed tomography (CT), magnetic resonance (MR) imaging including MR cholangiopancreatography (MRCP), ultrasound, and endoscopic retrograde cholangiopancreatography (ERCP) results were reviewed. The 2-tone duct sign and cork-of-wine-bottle sign were reviewed as indicators of intraductal tumor growth on CT/MR and MRCP/ERCP images, respectively.
A 2-tone duct sign was noted on the dynamic CT images (7/10, 70%) and on the MR imaging (5/8, 63%). The distal main pancreatic duct was dilated in all the patients except one, who had a branch duct lesion. A cork-of-wine-bottle sign was observed on the MRCP image (3/8, 38%) and on the ERCP image (3/6, 50%).
Intraductal tubulopapillary neoplasms are rare tumors showing characteristic imaging findings such as the 2-tone duct sign and the cork-of-wine-bottle sign that represent their intraductal growth.
本研究的目的是描述胰腺导管内管状乳头状肿瘤的影像学表现。
回顾性收集11例经病理证实为导管内管状乳头状肿瘤的胰腺肿瘤。回顾了动态对比增强计算机断层扫描（CT）、包括磁共振胰胆管造影（MRCP）的磁共振（MR）成像、超声和内镜逆行胰胆管造影（ERCP）结果。分别将双色调导管征和酒瓶塞征作为CT/MR和MRCP/ERCP图像上导管内肿瘤生长的指标进行回顾。
在动态CT图像上（7/10，70%）和MR成像上（5/8，63%）发现双色调导管征。除1例为分支导管病变外，所有患者的主胰管远端均扩张。在MRCP图像上（3/8，38%）和ERCP图像上（3/6，50%）观察到酒瓶塞征。
导管内管状乳头状肿瘤是罕见的肿瘤，具有双色调导管征和酒瓶塞征等特征性影像学表现，这些表现代表了肿瘤的导管内生长。
