Institut für Pharmazeutische Biologie, Heinrich-Heine-Universität, Universitätsstr. 1, D-40225 Düsseldorf, Germany.
Phytomedicine. 1996 Jan;2(3):193-8. doi: 10.1016/S0944-7113(96)80041-9.
In order to give guidelines for the characterization and standardization of plant material used for pharmacological, clinical and toxicological studies, suggestions are made how to handle extracts or preparations in which the active principles are known, extracts or preparations in which the active principles are unknown, and mixed (multi) preparations containing several raw drugs or extracts. For each category, practical examples of analytical methods are mentioned mainly based on HPLC fingerprint analysis.
为了为用于药理学、临床和毒理学研究的植物材料的特征描述和标准化提供指导，本文提出了如何处理已知活性成分的提取物或制剂、未知活性成分的提取物或制剂以及含有几种原料药或提取物的混合（多）制剂的建议。对于每种类别，主要基于 HPLC 指纹分析，提到了分析方法的实际示例。
