Institute of Robotics and Intelligent Systems, Zurich, Switzerland.
Adv Healthc Mater. 2013 Apr;2(4):591-8. doi: 10.1002/adhm.201200282. Epub 2012 Nov 29.
The surface properties of electrodeposited poly(pyrrole) (Ppy) doped with sodium dodecylbenzenesulphonate (NaDBS) are modified by two methods: addition of poly(ethylene glycol) (PEG) during the electrodeposition and through redox cycling post electrodeposition. X-ray photoelectron spectroscopy (XPS) was used to ascertain PEG incorporation and to analyze the change in the oxidation state of the polymer. Anodic cycling resulted in the formation of micrometer-sized surface cracks which increased the amount of Rhodamine-B dye adsorbed onto the surface, and played a role in decreasing the wettability of the surface. The change in surface wettability caused by these cracks was mitigated by the presence of PEG in the Ppy matrix. Compared to the incorporation of PEG, redox cycling was more effective in passively modulating the adhesion of NIH 3T3 fibroblast cells on the Ppy surface. Based on the attenuation of surface polarity of the Ppy surfaces by the incorporated PEG, a mechanism is proposed to explain the observed cell adhesion behavior.
通过两种方法对电沉积掺杂十二烷基苯磺酸钠（NaDBS）的聚吡咯（Ppy）的表面性能进行改性：在电沉积过程中添加聚乙二醇（PEG）和电沉积后进行氧化还原循环。X 射线光电子能谱（XPS）用于确定 PEG 的掺入并分析聚合物氧化态的变化。阳极循环导致形成微米级的表面裂纹，从而增加了 Rhodamine-B 染料吸附到表面的量，并在降低表面润湿性方面发挥了作用。Ppy 基质中存在 PEG 减轻了这些裂纹引起的表面润湿性变化。与 PEG 的掺入相比，氧化还原循环在被动调节 NIH 3T3 成纤维细胞在 Ppy 表面的粘附性方面更有效。根据掺入的 PEG 降低了 Ppy 表面极性，提出了一种解释观察到的细胞粘附行为的机制。
