Anatomy & Human Sciences, King's College London, London Bridge, London, SE1 1UL UK.
EPMA J. 2010 Sep;1(3):503-12. doi: 10.1007/s13167-010-0021-6. Epub 2010 Jun 9.
The presence of DNA and RNA circulating in human plasma and serum is described. The known sources of the DNA/RNA in blood, the ability of these nucleic acids to enter other cells and to express in the recipient cells are considered along with their relationship to metastases. The possible role(s) of the DNA/RNA in personalized clinical diagnosis, monitoring of treatment and prognosis in oncology are discussed.
本文描述了 DNA 和 RNA 存在于人类血浆和血清中的情况。考虑到血液中 DNA/RNA 的已知来源、这些核酸进入其他细胞并在受者细胞中表达的能力，以及它们与转移的关系，还讨论了这些核酸在个性化临床诊断、肿瘤治疗监测和预后中的可能作用。
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