Nikiforova N A, Moskalenko I P, Gaĭseniuk L A, Pozhidaeva O N
Med Radiol (Mosk). 1990 Mar;35(3):25-7.
A study was made of the level of reparative capacity of peripheral blood lymphocytes of cancer patients in response to DNA damaging R-radiation testing at a dose of 250 Gy before the next course of cancer chemotherapy. A low capacity of peripheral blood lymphocytes for reparation of DNA or its complete suppression is characteristic for most cancer patients irrespective of a nosological entity and the number of cancer chemotherapy courses in their history. The frequency of cancer patients with the initially suppressed capacity of peripheral blood lymphocytes for DNA reparation has an increasing tendency depending on the spreading of a process. These data can serve as an additional criterion of prognosis of complication during antitumor therapy.
对癌症患者外周血淋巴细胞的修复能力水平进行了研究，该研究是在下一疗程癌症化疗前，以250戈瑞的剂量进行DNA损伤R辐射测试时进行的。大多数癌症患者外周血淋巴细胞修复DNA的能力较低或完全受到抑制，这与疾病分类实体以及他们既往接受癌症化疗的疗程数无关。外周血淋巴细胞最初DNA修复能力受到抑制的癌症患者的频率，随着病情进展有增加的趋势。这些数据可作为抗肿瘤治疗期间并发症预后的额外标准。
