Rojas E, Scorza J V
Centro de Investigaciones Jose W. Torrealba, Trujillo, Venezuela.
Mem Inst Oswaldo Cruz. 1989 Jan-Mar;84(1):29-34. doi: 10.1590/s0074-02761989000100006.
Eight patients infected with Leishmania braziliensis were used for xenodiagnosis with Lutzomyia youngi, before and after specific antileishmanial treatment with "glucantime" and "gabbromycin". All of them infected sandflies fed on the borders of the skin lesions before the treatment, suggesting that infected persons might act as reservoirs of infection for an indoor-biting sandfly species. The negative results obtained by xenodiagnosis carried out after specific treatment of the same individuals indicated cure of the patients, and a reduction of risk for further intradomiciliary transmission.
八名感染巴西利什曼原虫的患者在使用“葡糖胺锑钠”和“加布罗霉素”进行特异性抗利什曼原虫治疗前后，均采用杨氏白蛉进行了虫媒接种诊断。在治疗前，所有感染的白蛉都在皮肤病变边缘取食，这表明感染者可能成为室内叮咬白蛉物种的感染源。对同一批个体进行特异性治疗后进行的虫媒接种诊断结果为阴性，表明患者已治愈，且进一步家庭内传播的风险降低。
