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在治愈患者的血液样本中或免疫治疗不同阶段存在巴西利什曼原虫。

Presence of Leishmania braziliensis in blood samples from cured patients or at different stages of immunotherapy.

作者信息

Guevara P, Rojas E, Gonzalez N, Scorza J V, Añez N, Valera M, Ramírez J L

机构信息

Grupo de Genética Molecular, Facultad de Ciencias, Universidad Central de Venezuela, Caracas, Venezuela.

出版信息

Clin Diagn Lab Immunol. 1994 Jul;1(4):385-9. doi: 10.1128/cdli.1.4.385-389.1994.

DOI:10.1128/cdli.1.4.385-389.1994
PMID:8556473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC368272/
Abstract

By using a PCR assay specific for Leishmania braziliensis in blood samples, we detected this parasite in patients cured by immunotherapy or at different stages of treatment. We also found the parasite in subjects who had never suffered leishmaniasis but who had lived in endemic areas and migrated to nonendemic ones many years ago. These results suggest that L. braziliensis infections are difficult to eradicate and that a clinical cure but rarely a complete elimination of the parasite is generally accomplished.

摘要

通过对血液样本使用针对巴西利什曼原虫的聚合酶链反应检测方法,我们在接受免疫治疗治愈的患者或处于不同治疗阶段的患者中检测到了这种寄生虫。我们还在从未患过利什曼病但曾生活在流行地区且多年前迁移到非流行地区的人群中发现了该寄生虫。这些结果表明,巴西利什曼原虫感染难以根除,通常实现的是临床治愈,但很少能完全清除寄生虫。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/1d987a55fb7f/cdli00004-0032-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/c9ae64527d87/cdli00004-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/eb9487ec031c/cdli00004-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/be4d051e3c52/cdli00004-0031-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/e08242673ed3/cdli00004-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/1d987a55fb7f/cdli00004-0032-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/c9ae64527d87/cdli00004-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/eb9487ec031c/cdli00004-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/be4d051e3c52/cdli00004-0031-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/e08242673ed3/cdli00004-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/622f/368272/1d987a55fb7f/cdli00004-0032-b.jpg

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