[马拉喀什大学医院收治的儿童社区获得性腹膜炎的细菌学研究]
[Bacteriology of community-acquired peritonitis in children treated in the university hospital of Marrakech].
作者信息
Mouaffak Y, Boutbaoucht M, Soraa N, Chabaa L, Salama T, Oulad Saiad M, Younous S
机构信息
Service d'anesthésie-réanimation pédiatrique, hôpital Mère-Enfant, CHU Mohammed VI, université Cadi Ayyad, rue Ibn Sina, Amerchich, Marrakech, Maroc.
出版信息
Ann Fr Anesth Reanim. 2013 Jan;32(1):60-2. doi: 10.1016/j.annfar.2012.10.031. Epub 2012 Nov 27.
INTRODUCTION
The available microbiological data on community-acquired peritonitis in children are inadequate, and antibiotic therapy is not consensual. Our work aims to study the bacteriology of peritonitis in children in our region and discuss the appropriate antibiotherapy.
PATIENTS AND METHODS
A descriptive study spread over one year. We collected cases of peritonitis in which a microbiological study of peritoneal fluid was performed.
RESULTS
Of 38 cases, the most frequently isolated bacteria is Escherichia coli (E. coli) (50%). Its sensitivity was 64% to amoxicillin-clavulanate, 93.33% to third generation cephalosporins (C3G) and 100% to ertapenem and aminozides.
CONCLUSION
We find a high rate of resistance of E. coli to amoxicillin-clavulanic acid. This prompts us to reconsider our therapeutic approach. We believe that the association C3G+aminoglycoside+metronidazole should be used first-line in the pediatric peritonitis in our context.
引言
关于儿童社区获得性腹膜炎的现有微生物学数据不足，抗生素治疗尚无共识。我们的工作旨在研究我们地区儿童腹膜炎的细菌学，并讨论适当的抗菌治疗方法。
患者与方法
一项为期一年的描述性研究。我们收集了进行腹膜液微生物学研究的腹膜炎病例。
结果
在38例病例中，最常分离出的细菌是大肠杆菌（E. coli）（50%）。其对阿莫西林-克拉维酸的敏感性为64%，对第三代头孢菌素（C3G）为93.33%，对厄他培南和氨基糖苷类为100%。
结论
我们发现大肠杆菌对阿莫西林-克拉维酸的耐药率很高。这促使我们重新考虑我们的治疗方法。我们认为，在我们的情况下，C3G+氨基糖苷类+甲硝唑联合应用应作为儿童腹膜炎的一线治疗方案。
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