Bazhar Samia, Benaissa Elmostafa, Ziad Fatima, Laamara Leila, Ben Lahlou Yassine, Chadli Mariama, Elouennass Mostafa
Department of Clinical Bacteriology, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco.
Research Team of Epidemiology and Bacterial Resistance, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco.
Access Microbiol. 2024 Oct 24;6(10). doi: 10.1099/acmi.0.000816.v5. eCollection 2024.
Peritonitis is characterized by acute inflammation of the peritoneum, often resulting from digestive organ perforation or intra-abdominal septic focus. It may be of either infectious or non-infectious origin. The bacteria involved are those of the digestive flora ( and anaerobes), while Gram-positive cocci and yeasts can be isolated in nosocomial infections. Our study aims to isolate and identify the germs involved in community-acquired peritonitis in order to assess their susceptibility to the antibiotics available in our country. This is a retrospective study of the bacteriological profile of community peritonitis in Rabat Morocco. A total of 150 adult patients with peritonitis were admitted and samples were collected intraoperatively for bacteriological examination between 1 July 2022 and 30 April 2023. Among the 150 patients, 101 (67.8%) were males and 49 (32.2%) were females, with a sex ratio (M/F) of 2 : 1. The mean age of the patients was 40.5 years±20.12. The distribution of bacteria was dominated by (44%). Overall, 70% of isolated exhibited resistance to ampicillin, whereas no resistance to ampicillin has been reported for . In the present study, we were interested in the bacteriological profile of community peritonitis in order to adapt the antibiotic therapy to our bacterial ecology. Our findings indicate a concerning trend of increasing resistance among to the commonly used amoxicillin/clavulanic acid combination in our clinical setting. Consequently, there is a need to reassess the empiric antibiotic prescribed for the management of community-acquired peritonitis.
腹膜炎的特征是腹膜急性炎症，通常由消化器官穿孔或腹腔内感染灶引起。它可能源于感染性或非感染性。涉及的细菌是消化菌群（和厌氧菌），而革兰氏阳性球菌和酵母菌可在医院感染中分离出来。我们的研究旨在分离和鉴定社区获得性腹膜炎中涉及的病菌，以评估它们对我国现有抗生素的敏感性。这是一项对摩洛哥拉巴特社区腹膜炎细菌学特征的回顾性研究。2022年7月1日至2023年4月30日期间，共有150例成年腹膜炎患者入院，并在术中采集样本进行细菌学检查。在这150例患者中，男性101例（67.8%），女性49例（32.2%），性别比（男/女）为2∶1。患者的平均年龄为40.5岁±20.12岁。细菌分布以（44%）为主。总体而言，分离出的70%的对氨苄西林耐药，而未报告对氨苄西林耐药。在本研究中，我们关注社区腹膜炎细菌学特征，以便使抗生素治疗适应我们的细菌生态。我们的研究结果表明，在我们的临床环境中，对常用的阿莫西林/克拉维酸组合耐药的趋势令人担忧。因此，有必要重新评估用于治疗社区获得性腹膜炎的经验性抗生素。
