Department of Pediatrics and Child Neuropsychiatry, Sapienza University of Rome, Rome, Italy.
Int J Cardiol. 2013 Sep 30;168(2):1108-14. doi: 10.1016/j.ijcard.2012.11.045. Epub 2012 Nov 30.
Lipid standards in Italy are lacking in children and adolescents whereas those for blood pressure (BP) were derived from US surveys.
In a 14-town community in Southern Italy 1657 (64%) of 2594 children aged 6-14 years were enrolled and anthropometric, BP, lipid and glucose serum levels were obtained.
Average systolic BP was 101 ± 11 (60-150) mm Hg and cholesterol (CholT) level was 156 ± 28 (57-264) mg/dl. There were positive (p<0.00001) age-trends for systolic BP and body mass index (BMI) in both genders whereas age-trends for CholT and heart rate were negative (p<0.00001). A negative age-trend in both genders was also seen for non-HDL cholesterol (p<0.03). Based on 95% percentile gender and age distributions, there were 177 (10.68%) hypertensive (HT) and 82 (4.94%) hypercholesterolemic (HC) children or adolescents. Univariately, HT had higher (p<0.00001) height, weight, BMI, arm circumference, hips, waist, diastolic BP and waist/height, whereas HC had higher LDL-, HDL and non-HDL-cholesterol and triglycerides (p<0.01). Systolic BP was predicted (r(2)=0.2810, p=0.00001) by age (t=2.319, p<0.0205), male gender (t=3.179, p<0.0015), glucose (t=2.357, p<0.0186), height (t=2.473, p<0.0135), arm circumference (t=3.313, p<0.0009) and heart rate (t=4.161, p<0.00001). CholT was related inversely (r(2)=0.1399, p=0.00001) to height (t=-3.928, p<0.0001), weight (t=-3.922, p<0.0001) and waist/height (t=-4.797, p<0.00001) and directly to BMI (t=3.064, p<0.0022), waist (t=5.149, p<0.0000), triglycerides (t=11.332, p<0.00001) and female gender (t=-2.041, p<0.0414).
In these Southern Italian children and adolescents systolic BP and CholT are related with anthropometric and other variables, not confined to height. BP is lower than previously reported.
意大利缺乏儿童和青少年的血脂标准，而血压（BP）标准则源自美国的调查。
在意大利南部的一个 14 个城镇的社区中，共有 2594 名 6-14 岁的儿童，其中 1657 名（64%）参与了研究，获得了他们的体格测量、血压、血脂和血糖水平数据。
平均收缩压为 101 ± 11（60-150）mmHg，胆固醇（CholT）水平为 156 ± 28（57-264）mg/dl。在男女两性中，收缩压和体重指数（BMI）均呈正相关（p<0.00001），而 CholT 和心率呈负相关（p<0.00001）。在两性中，非高密度脂蛋白胆固醇（非-HDL 胆固醇）也呈负相关（p<0.03）。基于 95%百分位性别和年龄分布，有 177 名（10.68%）儿童或青少年患有高血压（HT），82 名（4.94%）患有高胆固醇血症（HC）。单变量分析显示，HT 组的身高、体重、BMI、臂围、臀围、腰围、舒张压和腰高比更高（p<0.00001），而 HC 组的 LDL-、HDL-和非-HDL-胆固醇以及甘油三酯水平更高（p<0.01）。收缩压与年龄（t=2.319，p<0.0205）、性别（t=3.179，p<0.0015）、血糖（t=2.357，p<0.0186）、身高（t=2.473，p<0.0135）、臂围（t=3.313，p<0.0009）和心率（t=4.161，p<0.00001）呈正相关（r(2)=0.2810，p=0.00001）。CholT 与身高（t=-3.928，p<0.0001）、体重（t=-3.922，p<0.0001）和腰高比（t=-4.797，p<0.00001）呈负相关，与 BMI（t=3.064，p<0.0022）、腰围（t=5.149，p<0.0000）、甘油三酯（t=11.332，p<0.00001）和女性性别（t=-2.041，p<0.0414）呈正相关。
在这些意大利南部的儿童和青少年中，收缩压和 CholT 与体重和其他变量有关，而不仅仅与身高有关。血压比之前报道的要低。
