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[实验性蛛网膜下腔出血中的脑脊液动力学]

[Cerebrospinal fluid dynamics in experimental subarachnoid hemorrhage].

作者信息

Brinker T, Seifert V, Stolke D

机构信息

Neurochirurgische Klinik, Medizinischen Hochschule Hannover.

出版信息

Neurochirurgia (Stuttg). 1990 Mar;33(2):42-4.

PMID:2320198
Abstract

To investigate the acute effects on intracerebral pressure, intracranial reserve capacity and CSF absorption resistance, a subarachnoidal haemorrhage was induced experimentally in a cat by bolus injection or continuous infusion of autologous blood into the cisterna magna. Intracisternal bolus injection resulted in a brief steep increase in intracranial pressure. 30 or 60 minutes after the haemorrhage the median intracranial pressure is slightly increased, the reserve capacity markedly reduced and the CSF absorption resistance considerably enhanced. During intracisternal blood infusion there is a continuous intracerebral pressure rise that persists to the end of the infusion and decrease again within a short time. This intracranial pressure behaviour is due to the simultaneous reduction of intracranial reserve capacity and the increase in CSF absorption resistance during the blood infusion.

摘要

为研究对颅内压、颅内储备能力和脑脊液吸收阻力的急性影响,通过向猫的枕大池快速推注或持续输注自体血,在猫身上实验性诱导蛛网膜下腔出血。枕大池快速推注导致颅内压短暂急剧升高。出血后30或60分钟,颅内压中位数略有升高,储备能力显著降低,脑脊液吸收阻力大幅增强。在枕大池血液输注期间,颅内压持续升高,一直持续到输注结束,并在短时间内再次下降。这种颅内压变化是由于在血液输注期间颅内储备能力同时降低和脑脊液吸收阻力增加所致。

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