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耳内镜下脂肪鼓膜成形术疗效分析:哪些患者适合?

Fat myringoplasty outcome analysis with otoendoscopy: who is the suitable patient?

机构信息

2nd Academic ORL Department, Papageorgiou Hospital, Thessaloniki, Greece.

出版信息

Otol Neurotol. 2013 Jan;34(1):95-9. doi: 10.1097/MAO.0b013e318278c1e3.

Abstract

OBJECTIVE

This study evaluates the success of fat graft myringoplasty under local anesthesia in relation to the size and location of the perforation and the presence of myringosclerosis using otoendoscopy findings.

STUDY DESIGN

Prospective cohort study.

SETTING

Tertiary referral center.

MATERIALS AND METHODS

Eighty-two patients without history of previous ear surgery underwent a fat graft myringoplasty under local anesthesia and followed up for 6 months. The fat graft harvested from the ear lobe in all cases. Otoendoscopy was used to record preoperative perforation and postoperative course. Measurements on endoscopic findings performed with Adobe acrobat software. Factors assessed were perforation size, location and myringosclerosis preoperatively, and residual perforation and graft neoangiogenesis postoperatively. Pure tone audiogram preoperatively and postoperatively was performed.

RESULTS

Successful closure of the perforation was observed in 70 (85.36%) of 82 ears. The success rate significantly decreased when the size of perforation was more than 30% of the pars tensa. The anterior location was not a good prognostic factor for a successful procedure. Myringosclerosis did not correlate with the success rate of the procedure. Angiogenesis to the fat graft divided in 3 categories according to its origin: the handle of malleus, tympanic rim, and mixed with an equal distribution. The air conduction thresholds of 42 ears were slightly improved (mean, 9.3 dB), whereas the thresholds of 29 ears remained unchanged.

CONCLUSION

A fat graft myringoplasty achieves its highest success rate in perforations smaller than 30% of the pars tensa. Tympanosclerosis should not be a contraindication for fat grafting.

摘要

目的

本研究通过耳内镜检查结果,评估局部麻醉下脂肪移植鼓膜成形术治疗鼓膜穿孔的成功率与穿孔大小和位置以及鼓膜硬化症的关系。

研究设计

前瞻性队列研究。

设置

三级转诊中心。

材料和方法

82 例无既往耳部手术史的患者在局部麻醉下接受脂肪移植鼓膜成形术,并随访 6 个月。所有病例均从耳甲腔取脂肪移植物。使用耳内镜记录术前穿孔和术后过程。使用 Adobe acrobat 软件对内镜检查结果进行测量。评估的因素包括术前穿孔大小、位置和鼓膜硬化症,以及术后残余穿孔和移植物新生血管形成。术前和术后均进行纯音听阈测试。

结果

82 只耳朵中有 70 只(85.36%)观察到穿孔闭合。当穿孔大小超过鼓膜紧张部的 30%时,成功率显著降低。前位不是手术成功的良好预测因素。鼓膜硬化症与手术成功率无关。新生血管形成根据起源分为 3 类:锤骨柄、鼓膜环和混合分布。42 只耳朵的气导阈值略有改善(平均 9.3dB),而 29 只耳朵的阈值保持不变。

结论

在鼓膜紧张部小于 30%的穿孔中,脂肪移植鼓膜成形术的成功率最高。鼓膜硬化症不应成为脂肪移植的禁忌症。

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