Acar Mustafa, Yazıcı Demet, San Turhan, Muluk Nuray Bayar, Cingi Cemal
ENT Department, Yunus Emre State Hospital, Eskisehir, Turkey.
ENT Department, Tarsus State Hospital, İsmetpaşa Mh., 33440, Tarsus, Mersin, Turkey.
Eur Arch Otorhinolaryngol. 2015 Apr;272(4):861-866. doi: 10.1007/s00405-014-2890-0. Epub 2014 Jan 28.
The purpose of this study is to compare the success rates of fat-graft myringoplasties harvesting adipose grafts from different donor sites (ear lobule vs abdomen). The clinical records of 61 patients (24 males and 37 females) who underwent fat-plug myringoplasty (FPM) were reviewed retrospectively. Fat from ear lobule (FEL) and abdominal fat were used as graft materials. The impact of age, gender, systemic diseases, topography of the perforation, utilization of fat graft materials of different origin on the tympanic membrane closure rate and the effect of FPM on hearing gain was analyzed. Our tympanic membrane (TM) closure rate was 82 %. No statistical significant difference was observed regarding age, gender, comorbidities (septal deviation, hypertension and diabetes mellitus) or habits (smoking). Posterior TM perforations had significantly lower healing rate. The change in TM closure rate considering different adipose tissue donor sites was not statistically significant. The hearing gain of the patients was mostly below 20 dB. Fat-plug myringoplasty (FPM) is a safe, cost-effective and easy operation for selected patients. Abdominal fat graft is as effective as ear lobe fat graft on tympanic membrane healing, has cosmetic advantages and should be taken into consideration when planning fat as the graft source.
本研究的目的是比较从不同供区（耳垂与腹部）采集脂肪移植物进行脂肪移植鼓膜成形术的成功率。回顾性分析了61例行脂肪栓鼓膜成形术（FPM）患者（24例男性和37例女性）的临床记录。使用来自耳垂的脂肪（FEL）和腹部脂肪作为移植材料。分析了年龄、性别、全身性疾病、穿孔部位、不同来源脂肪移植材料的使用对鼓膜闭合率的影响以及FPM对听力增益的效果。我们的鼓膜（TM）闭合率为82%。在年龄、性别、合并症（鼻中隔偏曲、高血压和糖尿病）或习惯（吸烟）方面未观察到统计学上的显著差异。鼓膜后部穿孔的愈合率显著较低。考虑不同脂肪组织供区时TM闭合率的变化无统计学意义。患者的听力增益大多低于20dB。脂肪栓鼓膜成形术（FPM）对选定患者来说是一种安全、经济有效且简单的手术。腹部脂肪移植在鼓膜愈合方面与耳垂脂肪移植一样有效，具有美容优势，在将脂肪用作移植来源进行规划时应予以考虑。
