Sleep Laboratory, Division of Neuropsychiatry, Department of Psychiatry, University Hospitals of Geneva Geneva, Switzerland ; Department of Neuroscience, University of Geneva Geneva, Switzerland ; Swiss Center for Affective Sciences, University of Geneva Geneva, Switzerland.
Front Neurol. 2012 Nov 27;3:168. doi: 10.3389/fneur.2012.00168. eCollection 2012.
In this paper, we present two carefully documented cases of patients with sleep-related eating disorder (SRED), a parasomnia which is characterized by involuntary compulsive eating during the night and whose pathophysiology is not known. Using video-polysomnography, a dream diary and psychometric examination, we found that both patients present elevated novelty seeking and increased reward sensitivity. In light of new evidence on the mesolimbic dopaminergic implication in compulsive eating disorders, our findings suggest a role of an active reward system during sleep in the manifestation of SRED.
本文介绍了两例睡眠相关进食障碍（SRED）患者的详细病例，这是一种夜间无意识强迫性进食的睡眠障碍，其病理生理学尚不清楚。通过视频多导睡眠图、梦境日记和心理测量检查，我们发现这两名患者都表现出了较高的新奇寻求和增加的奖励敏感性。鉴于在强迫性进食障碍中涉及中脑边缘多巴胺能的新证据，我们的发现表明活跃的奖励系统在 SRED 表现中的作用。
