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经皮肺穿刺灌注化疗治疗广泛耐药肺结核。

Perfusing chemotherapy by percutaneous lung puncture in the treatment of extensive drug resistant pulmonary tuberculosis.

机构信息

Department of Tuberculosis, Institute of Tuberculosis Research, Nanjing Chest Hospital, 215 Guangzhou Road, Nanjing 210029, China;

出版信息

J Thorac Dis. 2012 Dec;4(6):624-8. doi: 10.3978/j.issn.2072-1439.2012.06.09.

Abstract

Although progress has been made to reduce global incidence of drug-susceptible tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) during the past decade threatens to undermine these advances. XDR-TB has been found to be associated with scarce therapeutic options and high mortality rates. We describe the first case of XDR-TB cured by percutaneous lung puncture and with post-hospital 4 years follow-up involving radiologic imaging and septum smear and TB culture. We also review the epidemiology, diagnosis and treatment of tuberculosis all the world.

摘要

尽管在降低全球范围内药物敏感性结核病的发病率方面取得了一定的进展,但过去十年中出现的耐多药(MDR)和广泛耐药(XDR)结核病(TB),有可能破坏这些进展。已经发现 XDR-TB 与治疗方法选择有限和高死亡率相关。我们描述了首例经皮肺穿刺治愈的 XDR-TB 病例,并在出院后进行了 4 年的随访,包括影像学检查、隔涂片和结核培养。我们还回顾了全球范围内结核病的流行病学、诊断和治疗。

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