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本文引用的文献

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Tuberculosis.结核病。
Lancet. 2011 Jul 2;378(9785):57-72. doi: 10.1016/S0140-6736(10)62173-3. Epub 2011 Mar 21.
2
Extensively drug-resistant tuberculosis at a tuberculosis specialist hospital in Shanghai, China: clinical characteristics and treatment outcomes.中国上海一家结核病专科医院的广泛耐药结核病:临床特征与治疗结果
Scand J Infect Dis. 2011 Apr;43(4):280-5. doi: 10.3109/00365548.2010.548080. Epub 2011 Jan 19.
3
Epidemiology of antituberculosis drug resistance 2002-07: an updated analysis of the Global Project on Anti-Tuberculosis Drug Resistance Surveillance.2002 - 2007年抗结核药物耐药性流行病学:全球抗结核药物耐药性监测项目的最新分析
Lancet. 2009 May 30;373(9678):1861-73. doi: 10.1016/S0140-6736(09)60331-7. Epub 2009 Apr 15.
4
Progress in tuberculosis control and the evolving public-health system in China.中国结核病控制进展与不断发展的公共卫生系统。
Lancet. 2007 Feb 24;369(9562):691-6. doi: 10.1016/S0140-6736(07)60316-X.
5
Clinical practice. Latent tuberculosis infection.临床实践。潜伏性结核感染。
N Engl J Med. 2002 Dec 5;347(23):1860-6. doi: 10.1056/NEJMcp021045.
6
An immunochromatographic serological assay for the diagnosis of Mycobacterium tuberculosis.一种用于诊断结核分枝杆菌的免疫层析血清学检测方法。
Comp Immunol Microbiol Infect Dis. 2002 Jan;25(1):21-7. doi: 10.1016/s0147-9571(01)00016-9.

经皮肺穿刺灌注化疗治疗广泛耐药肺结核。

Perfusing chemotherapy by percutaneous lung puncture in the treatment of extensive drug resistant pulmonary tuberculosis.

机构信息

Department of Tuberculosis, Institute of Tuberculosis Research, Nanjing Chest Hospital, 215 Guangzhou Road, Nanjing 210029, China;

出版信息

J Thorac Dis. 2012 Dec;4(6):624-8. doi: 10.3978/j.issn.2072-1439.2012.06.09.

DOI:10.3978/j.issn.2072-1439.2012.06.09
PMID:23205288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3506796/
Abstract

Although progress has been made to reduce global incidence of drug-susceptible tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) during the past decade threatens to undermine these advances. XDR-TB has been found to be associated with scarce therapeutic options and high mortality rates. We describe the first case of XDR-TB cured by percutaneous lung puncture and with post-hospital 4 years follow-up involving radiologic imaging and septum smear and TB culture. We also review the epidemiology, diagnosis and treatment of tuberculosis all the world.

摘要

尽管在降低全球范围内药物敏感性结核病的发病率方面取得了一定的进展,但过去十年中出现的耐多药(MDR)和广泛耐药(XDR)结核病(TB),有可能破坏这些进展。已经发现 XDR-TB 与治疗方法选择有限和高死亡率相关。我们描述了首例经皮肺穿刺治愈的 XDR-TB 病例,并在出院后进行了 4 年的随访,包括影像学检查、隔涂片和结核培养。我们还回顾了全球范围内结核病的流行病学、诊断和治疗。