National University of Singapore, Singapore.
Int J Psychophysiol. 2013 Feb;87(2):130-40. doi: 10.1016/j.ijpsycho.2012.11.011. Epub 2012 Nov 30.
Epidemiological studies have shown significant ethnic differences in coronary heart disease death rates with South Asians showing significantly greater coronary heart disease mortality than other groups.
This research examined ethnic differences in cardiovascular reactivity (CVR) among Chinese, Malays and Indians in Singapore as well as a sample of Indians living in India.
Experiment 1 examined differences across 303 Chinese, Malay and Indian undergraduates in Singapore, while Experiment 2 looked at differences in CVR between Indian participants from Singapore, and 145 Indians living in India. Systolic and diastolic blood pressure (SBP, DBP), heart rate (HR), cardiac index (CI) and total peripheral resistance index (TPRI) were measured during baselines and five laboratory tasks.
Ethnicity main effects for SBP and CI reactivity were obtained in Experiment 1, with Indians showing significantly lower BP and CI reactivity than the Chinese and Malays. Significant main effects for sex were found with females showing lower reactivity than males for TPRI, and greater reactivity than males for HR and CI. Experiment 2 found that participants from India showed higher reactivity for SBP, HR and CI, while Indian participants from Singapore showed higher TPRI reactivity. These differences, however, often varied by task.
These results point to differences in CVR among ethnic groups in Singapore as well as between Indians living in India and those living in Singapore. These differences may reflect cultural differences and need to be explored further with respect to their relationship to different rates of coronary heart disease among these groups.
流行病学研究表明,冠心病死亡率存在显著的种族差异,南亚人群的冠心病死亡率明显高于其他人群。
本研究旨在检验新加坡华人、马来人和印度人以及居住在印度的印度人之间心血管反应性(CVR)的种族差异。
实验 1 考察了新加坡 303 名华人、马来人和印度大学生之间的差异,实验 2 比较了新加坡的印度参与者和居住在印度的 145 名印度参与者之间的 CVR 差异。在基线和五个实验室任务期间测量了收缩压和舒张压(SBP、DBP)、心率(HR)、心输出量指数(CI)和总外周阻力指数(TPRI)。
实验 1 中,SBP 和 CI 反应的种族主效应得到了证实,印度人的血压和 CI 反应明显低于华人。实验 2 发现,女性的 TPRI 反应性低于男性,而 HR 和 CI 的反应性高于男性,存在显著的性别主效应。实验 2 发现,来自印度的参与者的 SBP、HR 和 CI 反应性较高,而来自新加坡的印度参与者的 TPRI 反应性较高。然而,这些差异通常因任务而异。
这些结果表明,新加坡不同种族群体之间以及居住在印度和新加坡的印度人之间的 CVR 存在差异。这些差异可能反映了文化差异,需要进一步探讨它们与这些群体中不同冠心病发病率之间的关系。