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宫颈癌中剂量率(MDR)近距离放疗中的半导体体内剂量学。

In vivo dosimetry with semiconductors in medium dose rate (MDR) brachytherapy for cervical cancer.

机构信息

Department of Medical Physics, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Jpn J Radiol. 2013 Mar;31(3):160-5. doi: 10.1007/s11604-012-0160-x. Epub 2012 Dec 5.

Abstract

PURPOSE

This study was performed to evaluate the role of in vivo dosimetry with semiconductor detectors in gynaecological medium dose rate brachytherapy, and to compare the actual doses delivered to organs at risk (as measured using in vivo dosimetry) with those calculated during treatment planning.

MATERIALS AND METHODS

Doses to the rectum and bladder were measured in a group of patients with cervical carcinoma using semiconductor detectors and compared to the doses calculated using a treatment planning system. 36 applications of brachytherapy at dose rates of 1.8-2.3 Gy/h were performed in the patients.

RESULTS

The mean differences between the measured and calculated doses were 3 % for the rectum and 11 % for the bladder.

CONCLUSIONS

The main reason for the differences between the measured and calculated doses was patient movement. To reduce the risk of large errors in the dose delivered, in vivo dosimetry should be performed in addition to treatment planning system computations.

摘要

目的

本研究旨在评估半导体探测器在妇科中剂量率近距离治疗中的体内剂量学作用,并比较使用体内剂量学测量的靶器官实际剂量与治疗计划中计算的剂量。

材料与方法

使用半导体探测器测量一组宫颈癌患者的直肠和膀胱剂量,并与治疗计划系统计算的剂量进行比较。对 36 例剂量率为 1.8-2.3 Gy/h 的近距离治疗应用进行了研究。

结果

直肠的测量剂量与计算剂量之间的平均差异为 3%,膀胱的平均差异为 11%。

结论

测量剂量与计算剂量之间差异的主要原因是患者移动。为了降低剂量输送中出现大误差的风险,除了治疗计划系统计算外,还应进行体内剂量学测量。

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