Kattapuram S V, Khurana J S, Scott J A, el-Khoury G Y
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
Skeletal Radiol. 1990;19(2):113-6. doi: 10.1007/BF00197616.
We report three patients with known primary tumor in whom radionuclide skeletal imaging for metastatic disease was normal with or without clinical symptomatology referable to this area. Magnetic resonance imaging (MRI) of the spine demonstrated focal areas of abnormal signal intensity in the vertebral bodies of these patients. In all three patients, biopsy confirmed metastatic disease. All the patients received radiation or chemotherapy depending upon the etiology. These preliminary data suggest that MR imaging may be useful in evaluating patients with known primary tumor in whom clinical suspicion persists despite a negative radionuclide bone scan.
我们报告了3例已知原发性肿瘤的患者，这些患者无论有无该区域相关的临床症状，其用于检测转移性疾病的放射性核素骨显像结果均为正常。脊柱磁共振成像（MRI）显示这些患者椎体存在局灶性异常信号强度区域。在所有3例患者中，活检均证实为转移性疾病。所有患者均根据病因接受了放疗或化疗。这些初步数据表明，对于已知原发性肿瘤且尽管放射性核素骨扫描结果为阴性但临床仍高度怀疑有转移的患者，磁共振成像可能有助于评估。
