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全球更新:瑞典。

Global update: Sweden.

机构信息

Karolinska Institutet, Karolinska University Hospital Huddinge, K57, SE 141 86 Stockholm, Sweden.

出版信息

Regen Med. 2012 Nov;7(6 Suppl):140-2. doi: 10.2217/rme.12.74.

Abstract

Swedish researchers have been very active in the stem cell field for many years. They have pioneered areas such as clinical treatment of Parkinson's disease, developmental biology including early stem cells, human embryonic stem cells, induced pluripotent stem cells and human mesenchymal stem cells. The Swedish Research Council and other funding organizations have been very positive for stem cell research, and there is a favorable law in Sweden regulating human embryonic stem cell research. Many groups have been active partners in projects funded by the European Commission. Clinical trials are ongoing with mesenchymal stem cells in graft versus host disease and osteogenesis imperfecta. Successful transplantations of trachea using a tissue-engineered product with cells cultured into a scaffold have been made recently. Optimizing the stem cell type for these constructs is ongoing.

摘要

瑞典的研究人员在干细胞领域活跃多年。他们开创了许多领域,如帕金森病的临床治疗、发育生物学,包括早期干细胞、人类胚胎干细胞、诱导多能干细胞和人类间充质干细胞。瑞典研究理事会和其他资助组织对干细胞研究持非常积极的态度,并且瑞典有一项有利于人类胚胎干细胞研究的法律。许多团体一直是欧盟委员会资助项目的积极合作伙伴。间充质干细胞在移植物抗宿主病和成骨不全症的临床试验正在进行中。最近,使用细胞培养到支架上的组织工程产品成功移植了气管。目前正在优化这些构建体的干细胞类型。

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