Pacific Parkinson's Research Centre, University of British Columbia & Vancouver Coastal Health, 2221 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada.
Transl Neurodegener. 2012 Jan 13;1(1):5. doi: 10.1186/2047-9158-1-5.
Functional imaging may be useful for both the early diagnosis as well as preclinical detection of neurodegenerative disease. Additionally, while structural imaging has traditionally been regarded as a tool to exclude alternate diagnoses, recent advances in magnetic resonance show promise for greater diagnostic specificity. The role of MR and radionuclide imaging in early diagnosis and preclinical detection of dementia and parkinsonism are reviewed here.
功能成像可能对神经退行性疾病的早期诊断和临床前检测都有用。此外,虽然结构成像传统上被视为排除其他诊断的工具,但磁共振的最新进展显示出提高诊断特异性的希望。本文回顾了磁共振和放射性核素成像在痴呆和帕金森病的早期诊断和临床前检测中的作用。