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抗精神病药物停药综合征:证据的叙述性综述及其纳入澳大利亚心理健康护理教科书的情况

Antipsychotic discontinuation syndromes: a narrative review of the evidence and its integration into Australian mental health nursing textbooks.

作者信息

Salomon Carmela, Hamilton Bridget

机构信息

Department of Nursing, School of Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.

出版信息

Int J Ment Health Nurs. 2014 Feb;23(1):69-78. doi: 10.1111/j.1447-0349.2012.00889.x. Epub 2012 Dec 5.

Abstract

In light of the high number of people discontinuing antipsychotics each year, it is essential that nurses develop a robust understanding of all aspects of the discontinuation experience. While there is a large body of published work documenting post-discontinuation relapse rates, less is known about other aspects of the discontinuation experience. This paper presents the results of a narrative review of international studies of antipsychotic discontinuation syndromes and their relevance to nursing practice. Four key mental health nursing textbooks used in student nurse education in Australia are examined to assess how this evidence has been incorporated into clinical recommendations. This review finds that the evidence for discontinuation syndromes could be more widely disseminated and applied than it is at present. Strikingly, this evidence has not been incorporated into key mental health nursing textbooks in Australia at all. Slow integration into nursing published work may be influenced by a number of clinical and research uncertainties. We consider the impact of this silence on key nursing roles of psycho-education and adverse event monitoring during antipsychotic discontinuation periods. Further robust research should be conducted into discontinuation syndromes as a matter of urgency. Given the high number of consumers potentially impacted upon by discontinuation syndromes, nurse authors and educators should consider revising key nursing textbooks to include the currently available information about discontinuation syndromes.

摘要

鉴于每年有大量患者停用抗精神病药物,护士深入了解停药过程的各个方面至关重要。虽然有大量已发表的研究记录了停药后的复发率,但对于停药过程的其他方面却知之甚少。本文介绍了一项关于抗精神病药物停药综合征的国际研究的叙述性综述结果及其与护理实践的相关性。研究分析了澳大利亚用于学生护士教育的四本主要心理健康护理教科书,以评估这些证据是如何纳入临床建议的。该综述发现,停药综合征的证据目前尚未得到广泛传播和应用。令人惊讶的是,这一证据在澳大利亚的主要心理健康护理教科书中根本没有体现。其融入护理文献的速度缓慢可能受到多种临床和研究不确定性的影响。我们考虑了这种沉默对在抗精神病药物停药期间进行心理教育和不良事件监测等关键护理工作的影响。迫切需要对停药综合征开展进一步的深入研究。鉴于大量消费者可能受到停药综合征的影响,护士作者和教育工作者应考虑修订关键护理教科书,纳入有关停药综合征的现有信息。

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