急性胃肠炎婴儿中杯状病毒的出现情况。

The occurrence of calicivirus in infants with acute gastroenteritis.

作者信息

Suzuki H, Konno T, Kutsuzawa T, Imai A, Tazawa F, Ishida N, Katsushima N, Sakamoto M

出版信息

J Med Virol. 1979;4(4):321-6. doi: 10.1002/jmv.1890040410.

Abstract

Calicivirus was detected in 8 (1.2%) of 647 hospitalized patients during a survey of acute gastroenteritis in infants and young children, conducted between December 1974 and September 1977. Morphologically calicivirus was approximately 30 nm in diameter with an easily recognizable staining "star of David" configuration. Its buoyant density in cesium chloride was 1.38-1.40 gm/ml. The serologic response to calicivirus by immune electron microscopy (IEM) was demonstrated only in paired sera from patients who shed the virus in their stools. The results suggest that calicivirus might be a cause of acute gastroenteritis in infants and young children.

摘要

在1974年12月至1977年9月对婴幼儿急性肠胃炎进行的一项调查中，647名住院患者中有8名（1.2%）检测出杯状病毒。从形态学上看，杯状病毒直径约30纳米，具有易于识别的染色“大卫之星”结构。其在氯化铯中的浮力密度为1.38 - 1.40克/毫升。仅在粪便中排出该病毒的患者的配对血清中，通过免疫电子显微镜（IEM）证实了对杯状病毒的血清学反应。结果表明，杯状病毒可能是婴幼儿急性肠胃炎的一个病因。