Hawley C M, Rigby R J, Boyle R S, Petrie J J
Department of Nephrology, Princess Alexandra Hospital, Woolloongabba, Brisbane, Queensland, Australia.
Am J Kidney Dis. 1990 Apr;15(4):364-8. doi: 10.1016/s0272-6386(12)80083-7.
Three patients who developed typical features of dialysis encephalopathy following renal transplantation are presented. No patient had evidence of overt neurological dysfunction pretransplantation. All patients were taking cyclosporine at the time of onset of neurological disease. Two patients died as a result of their neurological condition. The third patient made a satisfactory recovery. Factors responsible for the onset of dialysis encephalopathy in the renal posttransplantation period are discussed. We propose that cyclosporine may have been an important precipitating factor of the neurological syndrome of these patients.
本文报告了3例肾移植后出现典型透析性脑病特征的患者。所有患者在移植前均无明显神经功能障碍的证据。在神经疾病发作时，所有患者都在服用环孢素。2例患者因神经疾病死亡。第3例患者恢复良好。本文讨论了肾移植后发生透析性脑病的相关因素。我们认为环孢素可能是这些患者神经综合征的重要促发因素。
