Dhar Dinesh
Department of Orthopaedics, Nizwa Regional Referral Hospital, Sultanate of Oman.
J Coll Physicians Surg Pak. 2012 Dec;22(12):800-2.
Nearly all patients following fractures of bones develop sub-clinical form of fat embolism but the classical form of fat embolism syndrome (FES) presents with triad of respiratory, neurologic and dermal manifestations. Non-traumatic conditions can also have fat embolism, but the incidence is very low. The diagnosis is mainly clinical supported by laboratory and radiological finding. Treatment is mainly supportive with early stabilization of fractured bones. In most cases, prognosis is good if the condition is detected and treated early. High index of suspicion in polytrauma patient is the key to early diagnosis of this condition. This report describes two cases of FES, the second case being fulminant fat embolism with added mortality.
几乎所有骨折患者都会出现亚临床型脂肪栓塞,但典型的脂肪栓塞综合征(FES)表现为呼吸、神经和皮肤三联征。非创伤性情况也可发生脂肪栓塞,但发生率很低。诊断主要依靠临床症状,并由实验室和影像学检查结果支持。治疗主要是支持性治疗,并尽早对骨折进行固定。在大多数情况下,如果能早期发现并治疗,预后良好。对多发伤患者保持高度怀疑指数是早期诊断该病的关键。本报告描述了两例脂肪栓塞综合征病例,第二例为暴发性脂肪栓塞,增加了死亡率。