Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.
Int J Med Inform. 2013 Apr;82(4):230-8. doi: 10.1016/j.ijmedinf.2012.11.006. Epub 2012 Dec 4.
Pediatric asthma exacerbations account for >1.8 million emergency department (ED) visits annually. Asthma guidelines are intended to guide time-dependent treatment decisions that improve clinical outcomes; however, guideline adherence is inadequate. We examined whether an automatic disease detection system increases clinicians' use of paper-based guidelines and decreases time to a disposition decision.
We evaluated a computerized asthma detection system that triggered NHLBI-adopted, evidence-based practice to improve care in an urban, tertiary care pediatric ED in a 3-month (7/09-9/09) prospective, randomized controlled trial. A probabilistic system screened all ED patients for acute asthma. For intervention patients, the system generated the asthma protocol at triage for intervention patients to guide early treatment initiation, while clinicians followed standard processes for control patients. The primary outcome measures included time to patient disposition.
The system identified 1100 patients with asthma exacerbations, of which 704 had a final asthma diagnosis determined by a physician-established reference standard. The positive predictive value for the probabilistic system was 65%. The median time to disposition decision did not differ among the intervention (289 min; IQR = (184, 375)) and control group (288 min; IQR = (185, 375)) (p=0.21). The hospital admission rate was unchanged between intervention (37%) and control groups (35%) (p = 0.545). ED length of stay did not differ among the intervention (331 min; IQR = (226, 581)) and control group (331 min; IQR = (222, 516)) (p = 0.568).
Despite a high level of support from the ED leadership and staff, a focused education effort, and implementation of an automated disease detection, the use of the paper-based asthma protocol remained low and time to patient disposition did not change.
儿科哮喘发作每年导致超过 180 万次急诊部(ED)就诊。哮喘指南旨在指导随时间变化的治疗决策,以改善临床结果;然而,指南的依从性不足。我们研究了自动疾病检测系统是否会增加临床医生对纸质指南的使用并缩短处置决策的时间。
我们评估了一种计算机化的哮喘检测系统,该系统触发了 NHLBI 采用的、基于证据的实践,以改善城市三级保健儿科 ED 的护理。在一项为期 3 个月(7/09-9/09)的前瞻性、随机对照试验中,使用概率系统筛选所有 ED 患者的急性哮喘。对于干预患者,系统在分诊时生成哮喘方案,以指导早期治疗启动,而临床医生则遵循控制患者的标准流程。主要结局指标包括患者处置的时间。
该系统识别出 1100 例哮喘加重患者,其中 704 例患者的最终哮喘诊断由医生建立的参考标准确定。概率系统的阳性预测值为 65%。干预组(289 分钟;IQR = (184, 375))和对照组(288 分钟;IQR = (185, 375))之间的处置决策时间中位数没有差异(p=0.21)。干预组(37%)和对照组(35%)的住院率(p = 0.545)没有差异。ED 住院时间在干预组(331 分钟;IQR = (226, 581))和对照组(331 分钟;IQR = (222, 516))之间没有差异(p = 0.568)。
尽管得到了 ED 领导层和工作人员的大力支持、集中的教育努力以及自动疾病检测的实施,但纸质哮喘方案的使用仍然很低,患者处置的时间也没有改变。