Dexheimer Judith W, Abramo Thomas J, Arnold Donald H, Johnson Kevin, Shyr Yu, Ye Fei, Fan Kang-Hsien, Patel Neal, Aronsky Dominik
Division of Emergency Medicine, Cincinnati Children's, United States; Division of Biomedical Informatics, Cincinnati Children's, United States.
Department of Pediatrics, University of Arkansas for Medical Sciences, United States.
Int J Med Inform. 2014 Nov;83(11):805-13. doi: 10.1016/j.ijmedinf.2014.07.008. Epub 2014 Aug 8.
The use of evidence-based guidelines can improve the care for asthma patients. We implemented a computerized asthma management system in a pediatric emergency department (ED) to integrate national guidelines. Our objective was to determine whether patient eligibility identification by a probabilistic disease detection system (Bayesian network) combined with an asthma management system embedded in the workflow decreases time to disposition decision.
We performed a prospective, randomized controlled trial in an urban, tertiary care pediatric ED. All patients 2-18 years of age presenting to the ED between October 2010 and February 2011 were screened for inclusion by the disease detection system. Patients identified to have an asthma exacerbation were randomized to intervention or control. For intervention patients, asthma management was computer-driven and workflow-integrated including computer-based asthma scoring in triage, and time-driven display of asthma-related reminders for re-scoring on the electronic patient status board combined with guideline-compliant order sets. Control patients received standard asthma management. The primary outcome measure was the time from triage to disposition decision.
The Bayesian network identified 1339 patients with asthma exacerbations, of which 788 had an asthma diagnosis determined by an ED physician-established reference standard (positive predictive value 69.9%). The median time to disposition decision did not differ among the intervention (228 min; IQR=(141, 326)) and control group (223 min; IQR=(129, 316)); (p=0.362). The hospital admission rate was unchanged between intervention (25%) and control groups (26%); (p=0.867). ED length of stay did not differ among intervention (262 min; IQR=(165, 410)) and control group (247 min; IQR=(163, 379)); (p=0.818).
The control and intervention groups were similar in regards to time to disposition; the computerized management system did not add additional wait time. The time to disposition decision did not change; however the management system integrated several different information systems to support clinicians' communication.
采用循证指南可改善哮喘患者的护理。我们在一家儿科急诊科实施了一个计算机化哮喘管理系统,以整合国家指南。我们的目的是确定通过概率性疾病检测系统(贝叶斯网络)结合工作流程中嵌入的哮喘管理系统来识别患者是否符合条件,是否能缩短做出处置决定的时间。
我们在一家城市三级护理儿科急诊科进行了一项前瞻性随机对照试验。2010年10月至2011年2月期间到该急诊科就诊的所有2至18岁患者均通过疾病检测系统进行筛选以确定是否纳入。被确定为哮喘急性加重的患者被随机分为干预组或对照组。对于干预组患者,哮喘管理由计算机驱动并整合到工作流程中,包括在分诊时进行基于计算机的哮喘评分,以及在电子患者状态板上根据时间驱动显示哮喘相关提醒以便重新评分,并结合符合指南的医嘱集。对照组患者接受标准哮喘管理。主要结局指标是从分诊到做出处置决定的时间。
贝叶斯网络识别出1339例哮喘急性加重患者,其中788例经急诊科医生确定的参考标准诊断为哮喘(阳性预测值69.9%)。干预组(228分钟;四分位数间距=(141, 326))和对照组(223分钟;四分位数间距=(129, 316))做出处置决定的中位时间无差异;(p=0.362)。干预组(25%)和对照组(26%)的住院率无变化;(p=0.867)。干预组(262分钟;四分位数间距=(165, 410))和对照组(247分钟;四分位数间距=(163, 379))的急诊留观时间无差异;(p=0.818)。
在做出处置的时间方面,对照组和干预组相似;计算机化管理系统并未增加额外的等待时间。做出处置决定的时间没有改变;然而,该管理系统整合了几个不同的信息系统以支持临床医生之间的沟通。