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Comparative effectiveness research and patients with multiple chronic conditions.比较效果研究与患有多种慢性病的患者
N Engl J Med. 2011 Jun 30;364(26):2478-81. doi: 10.1056/NEJMp1100535. Epub 2011 Jun 22.
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Predictors of 4-year retention among African American and white community-dwelling participants in the UAB study of aging.非裔美国人和白人社区居住参与者在 UAB 老龄化研究中 4 年保留率的预测因素。
Gerontologist. 2011 Jun;51 Suppl 1(Suppl 1):S46-58. doi: 10.1093/geront/gnr024.
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Symptom experience in HIV-infected adults: a function of demographic and clinical characteristics.HIV 感染成年人的症状体验:与人口统计学和临床特征有关。
J Pain Symptom Manage. 2009 Dec;38(6):882-93. doi: 10.1016/j.jpainsymman.2009.05.013.
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Development and first validation of the COPD Assessment Test.COPD 评估测试的制定与首次验证。
Eur Respir J. 2009 Sep;34(3):648-54. doi: 10.1183/09031936.00102509.
5
Correlation between symptoms and function in older adults with comorbidity.患有合并症的老年人症状与功能之间的相关性。
J Am Geriatr Soc. 2009 Apr;57(4):676-82. doi: 10.1111/j.1532-5415.2009.02178.x.
6
A review of the prevalence and impact of multiple symptoms in oncology patients.肿瘤患者多种症状的患病率及影响综述。
J Pain Symptom Manage. 2009 Apr;37(4):715-36. doi: 10.1016/j.jpainsymman.2008.04.018. Epub 2008 Nov 20.
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Daily symptom burden in end-stage chronic organ failure: a systematic review.终末期慢性器官衰竭的每日症状负担:一项系统综述
Palliat Med. 2008 Dec;22(8):938-48. doi: 10.1177/0269216308096906. Epub 2008 Sep 18.
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Range and severity of symptoms over time among older adults with chronic obstructive pulmonary disease and heart failure.慢性阻塞性肺疾病和心力衰竭老年患者症状随时间的范围及严重程度。
Arch Intern Med. 2007 Dec 10;167(22):2503-8. doi: 10.1001/archinte.167.22.2503.
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Symptom burden: multiple symptoms and their impact as patient-reported outcomes.症状负担:多种症状及其作为患者报告结局的影响
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Evaluating measurement equivalence using the item response theory log-likelihood ratio (IRTLR) method to assess differential item functioning (DIF): applications (with illustrations) to measures of physical functioning ability and general distress.使用项目反应理论对数似然比(IRTLR)方法评估测量等价性,以评估项目功能差异(DIF):身体功能能力和一般痛苦测量的应用(附说明)
Qual Life Res. 2007;16 Suppl 1:43-68. doi: 10.1007/s11136-007-9186-4. Epub 2007 May 5.

社区居住的老年人群体的症状评估:简短症状筛查的心理测量学特性。

Measuring symptoms in community-dwelling older adults: the psychometric properties of a brief symptom screen.

机构信息

*University of California San Francisco, San Francisco, CA †Department of Biostatistics, School of Public Health, University of Alabama, Tuscaloosa, AL ‡Johns Hopkins Bloomberg School of Public Health, Baltimore, MD §Department of Medicine, School of Medicine, University of Alabama, Tuscaloosa, AL ∥Department of Medicine, School of Medicine, Vanderbilt University, Nashville, TN ¶Center on Aging and Health, Johns Hopkins University, Baltimore, MD.

出版信息

Med Care. 2013 Oct;51(10):949-55. doi: 10.1097/MLR.0b013e3182a53d1f.

DOI:10.1097/MLR.0b013e3182a53d1f
PMID:23969593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4084777/
Abstract

BACKGROUND

With aging, the probability of experiencing multiple chronic conditions has increased, along with symptoms associated with these conditions. Symptoms form a central component of illness burden, and distress. To date, most symptom measures have focused on a particular disease population.

OBJECTIVE

We aimed to develop and evaluate a simple symptom screen using data obtained from a representative sample of community-dwelling older adults.

METHODS

Psychometric analyses were conducted on 10 self-reported dichotomous symptom indicators collected during in-person interviews from a sample of 1000 community-dwelling older adults. Symptoms included shortness of breath, feeling tired or fatigued, problems with balance or dizziness, perceived weakness in legs, constipation, daily pain, stiffness, poor appetite, anxiety, and anhedonia.

RESULTS

Over one third of the individuals (37.4%) had 5 or more concurrent symptoms. Stiffness and feeling tired were the most common symptoms. Confirmatory factor analyses were performed on the 10 symptoms for single factor and bifactor (physical and affective) models of symptom reporting. Goodness-of-fit indices indicated better fit for the bifactor model (χdf=10=89.6; P<0.001), but the practical significance of the improvement in fit was negligible. Differential item functioning analyses showed some differences of relatively high magnitude in location parameters by race; however, because the differential item functioning was in different directions, the impact on the overall measure was most likely lessened.

CONCLUSIONS

Among community-dwelling older adults, a large proportion experienced multiple co-occurring symptoms. This Brief Symptom Screen can be used to quickly measure the overall symptom load in older adult populations, including those with multiple chronic conditions.

摘要

背景

随着年龄的增长,经历多种慢性疾病的可能性增加了,同时也出现了与这些疾病相关的症状。症状是疾病负担和痛苦的核心组成部分。迄今为止,大多数症状测量方法都集中在特定的疾病人群上。

目的

我们旨在开发和评估一种简单的症状筛查方法,该方法使用从代表性的社区居住老年人样本中获得的数据。

方法

对从 1000 名社区居住老年人的面对面访谈中收集的 10 个自我报告的二分症状指标进行心理测量学分析。症状包括呼吸急促、感到疲倦或疲劳、平衡或头晕问题、腿部无力感、便秘、每日疼痛、僵硬、食欲不振、焦虑和快感缺失。

结果

超过三分之一的个体(37.4%)有 5 个或更多的并发症状。僵硬和疲倦是最常见的症状。对 10 种症状进行了单因素和双因素(身体和情感)症状报告模型的验证性因子分析。拟合优度指数表明双因素模型的拟合更好(χdf=10=89.6;P<0.001),但拟合的实际改善意义不大。差异项目功能分析表明,在种族方面,位置参数存在一些相对较大的差异;然而,由于差异项目功能的方向不同,对整体测量的影响很可能减弱。

结论

在社区居住的老年人中,很大一部分人经历了多种同时发生的症状。这种简短症状筛查可以用于快速测量老年人群的整体症状负担,包括那些患有多种慢性疾病的人群。