Departments of Psychology and Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada T2N 1N4.
Compr Psychiatry. 2013 May;54(4):388-97. doi: 10.1016/j.comppsych.2012.10.012. Epub 2012 Dec 4.
Schizophrenia and bipolar disorder are typically separated in diagnostic systems. Behavioral, cognitive, and brain abnormalities associated with each disorder nonetheless overlap. We evaluated the diagnostic specificity of facial emotion recognition deficits in schizophrenia and bipolar disorder to determine whether select aspects of emotion recognition differed for the two disorders. The investigation used an experimental task that included the same facial images in an emotion recognition condition and an age recognition condition (to control for processes associated with general face recognition) in 27 schizophrenia patients, 16 bipolar I patients, and 30 controls. Schizophrenia and bipolar patients exhibited both shared and distinct aspects of facial emotion recognition deficits. Schizophrenia patients had deficits in recognizing angry facial expressions compared to healthy controls and bipolar patients. Compared to control participants, both schizophrenia and bipolar patients were more likely to mislabel facial expressions of anger as fear. Given that schizophrenia patients exhibited a deficit in emotion recognition for angry faces, which did not appear due to generalized perceptual and cognitive dysfunction, improving recognition of threat-related expression may be an important intervention target to improve social functioning in schizophrenia.
精神分裂症和双相情感障碍在诊断系统中通常是分开的。然而，与每种疾病相关的行为、认知和大脑异常有重叠。我们评估了精神分裂症和双相情感障碍患者的面部情绪识别缺陷的诊断特异性，以确定两种疾病的情绪识别是否存在特定方面的差异。该研究使用了一个实验任务，该任务包括在情绪识别条件和年龄识别条件（以控制与一般面部识别相关的过程）下的相同面部图像，共有 27 名精神分裂症患者、16 名双相 I 型患者和 30 名对照组参与。精神分裂症和双相情感障碍患者都表现出面部情绪识别缺陷的共同和独特方面。与健康对照组和双相情感障碍患者相比，精神分裂症患者在识别愤怒面部表情方面存在缺陷。与对照组参与者相比，精神分裂症和双相情感障碍患者更有可能将愤怒的面部表情错误标记为恐惧。鉴于精神分裂症患者在识别愤怒面孔方面存在缺陷，而这种缺陷不是由于普遍的感知和认知功能障碍引起的，因此改善对威胁相关表情的识别可能是改善精神分裂症患者社交功能的一个重要干预目标。
