Division for Social Research in Medicines and Health, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Res Social Adm Pharm. 2013 Nov-Dec;9(6):884-902. doi: 10.1016/j.sapharm.2012.11.002. Epub 2012 Dec 4.
Depression is one of the most commonly encountered mental health problems leading to significant morbidity and mortality and high medical and societal costs. Antidepressant prescribing in the UK has more than doubled in the last decade. There are a variety of factors that have been shown to affect a patient's experience of taking antidepressants The aim of this research was to explore patient narratives interviews about depression and its treatment in order to improve patient and health professional understanding of what it is like to use antidepressants.
This study involved a supplementary secondary qualitative analysis of 80 in-depth narrative interviews from Healthtalkonline. Patients' experiences of using medicines for depression were explored in the context of their social, occupational and emotional impact, to identify any additional issues and to clarify what type of information people want to find after being prescribed a medicine. The interviews were conducted by the University of Oxford and had received ethical approval and been consented and copyrighted for this purpose. Data were analyzed thematically.
The most prominent theme was the coexistence of several conflicting issues around the use of medicines and participants were mostly influenced by the reality of their experiences, beliefs, attitudes and interaction with health care. Antidepressants appear to occupy a central place in many people' lives. Many people described how their medicines had helped them and how this served as a reinforcement to continue taking them in order to maintain a "normal life." Those who had stopped taking their antidepressants were likely to have experienced adverse reactions and had unsatisfactory interactions with health care professionals. A lack of information about antidepressants was a major cause of dissatisfaction often shaping attitudes to antidepressants'.
People's experiences with antidepressant use have a major impact on treatment continuation and hence treatment outcomes. Further studies are needed on depressed patients' beliefs about their depression and treatment and how they relate to different stages of illness, their interactions with health care and their adherence to antidepressants.
抑郁症是最常见的精神健康问题之一，导致发病率和死亡率显著上升，医疗和社会成本高。在过去十年中，英国的抗抑郁药处方增加了一倍多。有各种因素已被证明会影响患者服用抗抑郁药的体验。本研究的目的是探讨患者对抑郁症及其治疗的叙述性访谈，以提高患者和卫生专业人员对使用抗抑郁药的理解。
这是对 Healthtalkonline 上 80 个深度叙述性访谈的补充二次定性分析。在探讨社会、职业和情感影响的背景下，研究了患者使用抗抑郁药的经验，以确定任何其他问题，并阐明人们在开处方后想要找到什么样的信息。访谈由牛津大学进行，已获得伦理批准，并为此目的同意并获得版权。数据采用主题分析。
最突出的主题是围绕使用药物存在几种相互矛盾的问题，参与者主要受到他们的经验、信念、态度和与医疗保健互动的现实影响。抗抑郁药似乎在许多人的生活中占据核心地位。许多人描述了他们的药物如何帮助他们，以及这如何强化他们继续服用以维持“正常生活”的意愿。那些停止服用抗抑郁药的人可能经历了不良反应，并且与医疗保健专业人员的互动不尽如人意。缺乏有关抗抑郁药的信息是导致不满的主要原因，这常常影响了人们对抗抑郁药的态度。
人们对抗抑郁药使用的体验对治疗的持续时间和治疗结果有重大影响。需要进一步研究抑郁症患者对其抑郁症和治疗的信念，以及这些信念如何与疾病的不同阶段、他们与医疗保健的互动以及他们对抗抑郁药的依从性相关。
