Department of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey.
Cardiol J. 2012;19(6):597-602. doi: 10.5603/cj.2012.0111.
There are few studies about predictors of ST elevation myocardial infarction (STEMI) in young patients. High red cell distribution width (RDW) levels were associated with adverse outcomes in patients with STEMI. We aimed to investigate the relationship between RDW and STEMI in young patients.
This study included 370 patients who presented to our hospital with acute myocardial infarction (Group 1: 198 young patients, 〈 45 ages for male, 〈 55 ages for female, Group 2: 172 elderly patients) and 156 adults with normal coronary angiography as a control group (Group 3: 91 young patients, 〈 45 ages for male, 〈 55 ages for female, Group 4: 65 elderly patients).
Compared with Group 3, Group 1 had a significantly higher value of RDW (Group 1 RDW 14.1 ± 1.1%, Group 3 RDW 13.4 ± 0.9, p1 〈 0.01). Value of RDW was similar both of Group 2 and 4 (Group 2 RDW 13.7 ± 1.2, Group 4 RDW 13.5 ± 0.9, p2 = 0.1). After multivariate analysis, high levels of RDW were independent predictors of STEMI in young patients (OR: 0.337, p 〈 0.01) together with gender (OR: 3.725, p 〈 0.01), history of hyperlipidemia (OR: 25.172, p 〈 0.01) and high density lipoprotein cholesterol (OR: 1.088, p 〈 0.01).
High levels of RDW were associated with STEMI in young patients. We think that RDW is a widely available marker with no additional costs, in contrast to other novel markers of cardiovascular risk.
关于年轻患者 ST 段抬高型心肌梗死（STEMI）预测因子的研究较少。高红细胞分布宽度（RDW）水平与 STEMI 患者的不良预后相关。我们旨在研究 RDW 与年轻患者 STEMI 的关系。
本研究纳入了 370 名因急性心肌梗死就诊于我院的患者（第 1 组：198 名年轻患者，男性〈45 岁，女性〈55 岁；第 2 组：172 名老年患者）和 156 名接受正常冠状动脉造影的成年人作为对照组（第 3 组：91 名年轻患者，男性〈45 岁，女性〈55 岁；第 4 组：65 名老年患者）。
与第 3 组相比，第 1 组的 RDW 值明显较高（第 1 组 RDW 14.1 ± 1.1%，第 3 组 RDW 13.4 ± 0.9%，p1〈0.01）。第 2 组和第 4 组的 RDW 值相似（第 2 组 RDW 13.7 ± 1.2%，第 4 组 RDW 13.5 ± 0.9%，p2=0.1）。多因素分析后，高 RDW 水平是年轻患者 STEMI 的独立预测因子（OR：0.337，p〈0.01），与性别（OR：3.725，p〈0.01）、高脂血症史（OR：25.172，p〈0.01）和高密度脂蛋白胆固醇（OR：1.088，p〈0.01）有关。
高 RDW 水平与年轻患者 STEMI 相关。我们认为，RDW 是一种广泛可用的标志物，与其他心血管风险的新型标志物相比，它没有额外的成本。
