Department of Physical Medicine and Rehabilitation, University of Michigan, 325 East Eisenhower Parkway, Ann Arbor, Michigan 48108, USA.
Muscle Nerve. 2013 Apr;47(4):497-503. doi: 10.1002/mus.23618. Epub 2012 Dec 6.
Nerve conduction studies provide information regarding the status of peripheral nerves, but relationships with sensorimotor capacities that influence mobility have not been defined.
A secondary analysis was conducted on data from 41 older subjects (20 women and 21 men, age 69.1 ± 8.3 years), including 25 with diabetic neuropathy of varying severity and 16 without diabetes or neuropathy. Measurements included routine fibular motor nerve conduction studies and laboratory-based determination of ankle inversion/eversion proprioceptive thresholds and ankle inversion/eversion motor function.
Independent of age, fibular amplitude correlated robustly with ankle inversion/eversion proprioceptive thresholds (R(2) = 0.591, P < 0.001), moderately with ankle inversion and eversion rates of torque generation (R(2) = 0.216; P = 0.004 and R(2) = 0.200; P = 0.006, respectively), and more strongly when fibular motor amplitude was normalized for body mass index (R(2) = 0.350; P < 0.001 and R(2) = 0.275; P = 0.001).
Fibular motor amplitude was strongly associated with ankle sensorimotor capacities that influence lateral balance and recovery from perturbations during gait. The results suggest that nerve conduction study measures have potential for an expanded clinical role in evaluating mobility function in the population studied.
神经传导研究提供了有关周围神经状况的信息，但与影响运动能力的感觉运动能力之间的关系尚未确定。
对 41 名老年受试者（20 名女性和 21 名男性，年龄 69.1 ± 8.3 岁）的数据进行了二次分析，其中 25 名患有不同严重程度的糖尿病性周围神经病变，16 名无糖尿病或周围神经病变。测量包括常规腓骨运动神经传导研究以及基于实验室的踝关节内翻/外翻本体感觉阈值和踝关节内翻/外翻运动功能的测定。
与年龄无关，腓骨振幅与踝关节内翻/外翻本体感觉阈值呈强相关（R² = 0.591，P < 0.001），与踝关节内翻和外翻扭矩产生率中度相关（R² = 0.216；P = 0.004 和 R² = 0.200；P = 0.006），当腓骨运动幅度按体重指数进行归一化时相关性更强（R² = 0.350；P < 0.001 和 R² = 0.275；P = 0.001）。
腓骨运动幅度与影响侧向平衡和从步态中恢复的踝关节感觉运动能力密切相关。结果表明，神经传导研究测量值有可能在评估所研究人群的移动功能方面发挥更大的临床作用。
