Xia Zheng-Xiang, Tang Zhong-Yan, An Rui, Chen Ye, Zhang Yi-Zhu, Wang Xin-Hong
School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yao Xue Xue Bao. 2012 Sep;47(9):1183-6.
A new and a known anthraquinone glycosides were isolated from the ethanol extract of the roots of Rheum officinale Baill. The extract was purified by various chromatographies, such as silica gel, Sephadex LH-20, RP-C18 column chromatography and HPLC. Two compounds were identified by the spectroscopic techniques of NMR, MS, and chemical method. In addition, they were tested for their cytotoxic effects against HepG2 cell. Unfortunately, they showed no or weak activity.
从掌叶大黄根的乙醇提取物中分离出一种新的和一种已知的蒽醌苷。提取物通过各种色谱法进行纯化，如硅胶柱色谱、葡聚糖凝胶LH-20柱色谱、反相C18柱色谱和高效液相色谱。通过核磁共振、质谱等光谱技术和化学方法鉴定了两种化合物。此外，还测试了它们对肝癌细胞HepG2的细胞毒性作用。遗憾的是，它们没有显示出活性或活性较弱。
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