Department of Cardiovascular Surgery, Sakakibara Heart institute, Tokyo, Japan.
Department of Cardiovascular Surgery, Sakakibara Heart institute, Tokyo, Japan.
J Thorac Cardiovasc Surg. 2014 Jan;147(1):290-4. doi: 10.1016/j.jtcvs.2012.11.007. Epub 2012 Dec 8.
We sought to evaluate surgical outcomes of type A acute aortic dissection in elderly patients.
Between January 2004 and July 2011, 422 patients underwent emergency open surgery for type A acute aortic dissection at our institution. Of those, 124 patients who were ≥75 years (mean age, 78.6 ± 3.4 years) were reviewed. We also reviewed 26 patients (≥75 years old) who were diagnosed with acute aortic dissection at our institution during the same period but who did not undergo surgery. We analyzed early and late outcomes of surgical and nonsurgical patients.
The operative mortality was 4.8% (6/124), and the incidences of stroke and prolonged hospital stay (>30 days) were 17.7% (22/124) and 20.1% (25/124), respectively. The actuarial survivals at 1, 3, and 5 years were 89.3%, 84.7%, and 79.1%, respectively. Predictors of stroke are preoperative cardiopulmonary resuscitation (odds ratio, 17.5; 95% confidence interval, 3.1-98.9; P = .001) and previous cardiac surgery (odds ratio, 14.0; 95% confidence interval, 1.2-164.7; P = .036). The 30-day or in-hospital mortality of patients who were indicated for surgery but refused surgery was 63.6% (7/11).
Emergency open surgery for type A acute aortic dissection in elderly patients resulted in a low mortality but high incidences of stroke and prolonged hospital stay. Preoperative cardiopulmonary resuscitation and previous cardiac surgery were significant predictors of stroke. Emergency surgery is still the primary option for most elderly patients with acute aortic dissection.
评估老年急性 A 型主动脉夹层患者的手术结果。
2004 年 1 月至 2011 年 7 月期间,我院对 422 例急性 A 型主动脉夹层患者进行了急诊开放手术。其中 124 例患者年龄≥75 岁(平均年龄 78.6±3.4 岁)。我们还回顾了同期在我院诊断为急性主动脉夹层但未接受手术的 26 例(≥75 岁)患者。我们分析了手术和非手术患者的早期和晚期结果。
手术死亡率为 4.8%(6/124),脑卒中发生率和住院时间延长(>30 天)发生率分别为 17.7%(22/124)和 20.1%(25/124)。术后 1、3 和 5 年的生存率分别为 89.3%、84.7%和 79.1%。脑卒中的预测因素是术前心肺复苏(比值比,17.5;95%置信区间,3.1-98.9;P=0.001)和既往心脏手术(比值比,14.0;95%置信区间,1.2-164.7;P=0.036)。手术指征但拒绝手术的患者 30 天或住院死亡率为 63.6%(7/11)。
老年急性 A 型主动脉夹层患者行急诊开放手术死亡率较低,但脑卒中发生率和住院时间延长。术前心肺复苏和既往心脏手术是脑卒中的显著预测因素。对于大多数老年急性主动脉夹层患者,急诊手术仍然是主要选择。