Division of Adolescent Medicine, Department of Medicine, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA.
JAMA Pediatr. 2013 Feb;167(2):149-55. doi: 10.1001/2013.jamapediatrics.12.
To investigate the association between overeating (without loss of control) and binge eating (overeating with loss of control) and adverse outcomes.
Prospective cohort study.
Adolescents and young adults living throughout the United States.
Sixteen thousand eight hundred eighty-two males and females participating in the Growing Up Today Study who were 9 to 15 years old at enrollment in 1996.
Overeating and binge eating assessed via questionnaire every 12 to 24 months between 1996 and 2005.
Risk of becoming overweight or obese, starting to binge drink frequently, starting to use marijuana, starting to use other drugs, and developing high levels of depressive symptoms. Generalized estimating equations were used to estimate associations. All models controlled for age and sex; additional covariates varied by outcome.
Among this large cohort of adolescents and young adults, binge eating was more common among females than males. In fully adjusted models, binge eating, but not overeating, was associated with incident overweight/obesity (odds ratio, 1.73; 95% CI, 1.11-2.69) and the onset of high depressive symptoms (odds ratio, 2.19; 95% CI, 1.40-3.45). Neither overeating nor binge eating was associated with starting to binge drink frequently, while both overeating and binge eating predicted starting to use marijuana and other drugs.
Although any overeating, with or without loss of control, predicted the onset of marijuana and other drug use, we found that binge eating is uniquely predictive of incident overweight/obesity and the onset of high depressive symptoms. These findings suggest that loss of control is an important indicator of severity of overeating episodes.
探讨非失控性暴食(无失控感的暴食)和失控性暴食(有失控感的暴食)与不良结局之间的关系。
前瞻性队列研究。
居住在美国各地的青少年和年轻成年人。
1996 年入组时年龄为 9 至 15 岁的 1682 名男性和女性,参与今日成长研究。
1996 年至 2005 年期间,通过问卷每 12 至 24 个月评估一次暴食和暴食行为。
超重或肥胖、开始频繁狂饮、开始使用大麻、开始使用其他毒品以及出现高水平抑郁症状的风险。使用广义估计方程来估计关联。所有模型均控制年龄和性别;根据结果,其他协变量也有所不同。
在这个大型青少年和年轻成年人队列中,女性暴食的发生率高于男性。在完全调整的模型中,暴食(而非暴食)与超重/肥胖的发生有关(比值比,1.73;95%置信区间,1.11-2.69),以及出现重度抑郁症状的开始(比值比,2.19;95%置信区间,1.40-3.45)。暴食和非暴食均与频繁狂饮的开始无关,而暴食和非暴食均预测开始使用大麻和其他毒品。
尽管任何暴食(有或无失控感)都预示着大麻和其他药物的使用开始,但我们发现,暴食行为是超重/肥胖和出现重度抑郁症状的独特预测因素。这些发现表明,失控是暴食发作严重程度的一个重要指标。