The Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.
Cancer Discov. 2012 Dec;2(12):1087-90. doi: 10.1158/2159-8290.CD-12-0424.
We outline an integrative approach to extend the boundaries of molecular cancer epidemiology by integrating modern and rapidly evolving "omics" technologies into state-of-the-art molecular epidemiology. In this way, one can comprehensively explore the mechanistic underpinnings of epidemiologic observations in cancer risk and outcome. We highlight the exciting opportunities to collaborate across large observational studies and to forge new interdisciplinary collaborative ventures.
我们概述了一种综合方法，通过将现代和快速发展的“组学”技术整合到最先进的分子流行病学中，来扩展分子癌症流行病学的边界。通过这种方式，可以全面探索癌症风险和结果中流行病学观察的机制基础。我们强调了跨大型观察性研究进行合作以及开创新的跨学科合作的令人兴奋的机会。
