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一名13岁女孩非综合征性遗传性牙龈纤维瘤病的诊断与治疗:罕见病例报告

Diagnosis and management of nonsyndromic hereditary gingival fibromatosis in a 13 year old girl: Report of a rare case.

作者信息

Goyal Lata, Bey Afshan, Gupta N D, Varshney Amitabh

机构信息

Department of Periodontics and Community Dentistry, Dr. Z. A. Dental College, Aligarh Muslim University, Aligarh, India.

出版信息

Contemp Clin Dent. 2012 Sep;3(Suppl 2):S210-3. doi: 10.4103/0976-237X.101097.

DOI:10.4103/0976-237X.101097
PMID:23230366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3514947/
Abstract

Hereditary gingival fibromatosis is a rare condition characterized by various degree of gingival overgrowth. It usually develops as an isolated disorder but can manifest with multisystem syndrome. We are here presenting a case of a 13-year-old girl who presented with severe enlargement of gingiva covering all most the entire crown involving both maxillary and mandibular arches. Differential diagnosis includes drug-induced and idiopathic gingival enlargement. Excess gingival tissue was removed by full mouth gingivectomy and sent for histopathological examination. Postoperative course was uneventful and patient's esthetics improved significantly. A 12 month postoperative period shows no recurrence.

摘要

遗传性牙龈纤维瘤病是一种罕见的疾病,其特征为不同程度的牙龈过度生长。它通常作为一种孤立性疾病出现,但也可伴有多系统综合征。我们在此报告一例13岁女孩的病例,该女孩出现严重的牙龈肿大,几乎覆盖了上颌和下颌牙弓的所有牙冠。鉴别诊断包括药物性和特发性牙龈肿大。通过全口牙龈切除术切除多余的牙龈组织,并送去做组织病理学检查。术后过程平稳,患者的美观度有显著改善。术后12个月未出现复发。

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Hereditary gingival fibromatosis: a systematic review.遗传性牙龈纤维瘤病:一项系统综述。
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A mutation in the SOS1 gene causes hereditary gingival fibromatosis type 1.SOS1基因的突变会导致1型遗传性牙龈纤维瘤病。
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