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遗传性牙龈纤维瘤病:一例罕见的同胞病例报告及其二极管激光治疗

Hereditary Gingival Fibromatosis: A Report of a Rare Case in Siblings and Its Management Using Diode Laser.

作者信息

Dureja Divya, Sharma Himani, Agarwal Mrinalini, Srivastava Saransh, Tandon Priyanka

机构信息

Department of Periodontology, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.

Department of Periodontology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.

出版信息

Contemp Clin Dent. 2020 Jul-Sep;11(3):290-293. doi: 10.4103/ccd.ccd_133_19. Epub 2020 Nov 26.

DOI:10.4103/ccd.ccd_133_19
PMID:33776359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7989762/
Abstract

Hereditary gingival fibromatosis (HGF) is a proliferative fibrous lesion causing severe gingival enlargement, affecting the esthetics, as well as posing various periodontal problems. This case report addresses the diagnosis and treatment of one such rare case of HGF where the patient presented with generalized diffuse gingival enlargement involving the maxillary and mandibular arches extending on the buccal and lingual/palatal surfaces and covering the incisal/occlusal third of the tooth, resulting in altered esthetics, difficulty in speech, and mastication. Gingivectomy was carried out in all the four quadrants using diode laser. The healing was uneventful; the patient was satisfied with her esthetics and was able to resume her oral hygiene practices. Even though recurrence cannot be predicted, the risk of recurrence can be outweighed with the psychological and functional benefits. Long-term follow-up will be required to evaluate the predictability of the different surgical techniques.

摘要

遗传性牙龈纤维瘤病(HGF)是一种增生性纤维病变,可导致严重的牙龈肿大,影响美观,并引发各种牙周问题。本病例报告阐述了一例罕见的HGF病例的诊断和治疗情况,该患者表现为全口弥漫性牙龈肿大,累及上颌和下颌牙弓,延伸至颊侧及舌侧/腭侧表面,覆盖牙齿的切缘/咬合面三分之一,导致美观改变、言语困难和咀嚼困难。使用二极管激光对四个象限均进行了牙龈切除术。愈合过程顺利;患者对美观效果满意,能够恢复口腔卫生习惯。尽管无法预测复发情况,但心理和功能方面的益处可超过复发风险。需要进行长期随访以评估不同手术技术的可预测性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/115d/7989762/92bfdc961606/CCD-11-290-g007.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/115d/7989762/ad5bbdadea9a/CCD-11-290-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/115d/7989762/c693269e1b5b/CCD-11-290-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/115d/7989762/c4adbefe9b1a/CCD-11-290-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/115d/7989762/3d75c5f038b6/CCD-11-290-g003.jpg
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本文引用的文献

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2
Hereditary gingival fibromatosis: Characteristics and treatment approach.遗传性牙龈纤维瘤病:特征与治疗方法
J Clin Exp Dent. 2017 Apr 1;9(4):e599-e602. doi: 10.4317/jced.53644. eCollection 2017 Apr.
3
Analysis of mutations in the SOS-1 gene in two Polish families with hereditary gingival fibromatosis.分析两个波兰遗传性牙龈纤维瘤病家系 SOS-1 基因突变。
Oral Dis. 2017 Oct;23(7):983-989. doi: 10.1111/odi.12684. Epub 2017 May 22.
4
Gingival fibromatosis: clinical, molecular and therapeutic issues.牙龈纤维瘤病:临床、分子及治疗问题
Orphanet J Rare Dis. 2016 Jan 27;11:9. doi: 10.1186/s13023-016-0395-1.
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Comparative evaluation of healing after gingivectomy with electrocautery and laser.电灼术与激光牙龈切除术后愈合情况的比较评估
J Oral Biol Craniofac Res. 2015 May-Aug;5(2):69-74. doi: 10.1016/j.jobcr.2015.04.005. Epub 2015 Jun 12.
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Hereditary gingival fibromatosis with distinct dental, skeletal and developmental abnormalities.伴有明显牙齿、骨骼和发育异常的遗传性牙龈纤维瘤病。
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