Onitiri A C, Sander M, Boyo A E
Trop Geogr Med. 1979 Dec;31(4):547-51.
In response to the growing demand for lipid profiles in Nigerian patients with suspected ischaemic heart disease, cerebro-vascular accident and hypertension, serum lipoprotein electrophoresis based on ozone-Schiff staining technique and densitometric scanning has been developed. Out of 93 serum samples 80 showed three distinct bands in the electrophoretic patterns; nine showed two distinct bands and four had unusual migration characteristics. Mean percentages of the three bands in the common pattern were 43.5, 22.8, and 33.7 for alpha pre-beta and beta lipoproteins respectively. The relative preponderance of alpha lipoproteins in Africans contrasts with the findings in Europeans. It supports the view that high serum alpha lipoproteins may be protective against ischaemic heart disease in contrast to the atherogenic role of beta lipoproteins.
针对尼日利亚疑似患有缺血性心脏病、脑血管意外和高血压患者对血脂谱检测需求的不断增长，基于臭氧 - 席夫染色技术和光密度扫描的血清脂蛋白电泳方法已被开发出来。在93份血清样本中，80份在电泳图谱上显示出三条清晰的条带；9份显示出两条清晰的条带，4份具有异常的迁移特征。常见图谱中三条带的平均百分比分别为：α脂蛋白43.5%、前β脂蛋白22.8%和β脂蛋白33.7%。非洲人α脂蛋白相对占优势，这与欧洲人的研究结果形成对比。这支持了这样一种观点，即与β脂蛋白的致动脉粥样硬化作用相反，高血清α脂蛋白可能对缺血性心脏病具有保护作用。
