注射新型男性抗生育剂“SMA”后大鼠输精管的组织学变化及其可逆性
Histological changes in the vas deferens of rats after injection of a new male antifertility agent "SMA" and its reversibility.
作者信息
Sethi N, Srivastava R K, Singh R K
机构信息
Division of Toxicology, Central Drug Research Institute, Lucknow, India.
出版信息
Contraception. 1990 Mar;41(3):333-9. doi: 10.1016/0010-7824(90)90074-6.
PMID:2323221
Abstract
A new male antifertility agent, styrene maleic anhydride (SMA) dissolved in dimethyl sulphoxide (DMSO), was injected into the vas deferens of rats. The morphological changes detected were confined only to the mucosa. After four weeks, the vas deferens lumen was flushed with the solvent DMSO, and the mucosal structures returned to normal.
摘要
一种新的男性抗生育剂，即溶解于二甲基亚砜（DMSO）中的苯乙烯马来酸酐（SMA），被注射到大鼠的输精管中。检测到的形态学变化仅局限于黏膜。四周后，用溶剂二甲基亚砜冲洗输精管腔，黏膜结构恢复正常。
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