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合成大麻与呼吸抑制。

Synthetic cannabis and respiratory depression.

作者信息

Jinwala Felecia N, Gupta Mayank

机构信息

Department of Psychiatry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854, USA.

出版信息

J Child Adolesc Psychopharmacol. 2012 Dec;22(6):459-62. doi: 10.1089/cap.2011.0122.

DOI:10.1089/cap.2011.0122
PMID:23234589
Abstract

In recent years, synthetic cannabis use has been increasing in appeal among adolescents, and its use is now at a 30 year peak among high school seniors. The constituents of synthetic cannabis are difficult to monitor, given the drug's easy accessibility. Currently, 40 U.S. states have banned the distribution and use of some known synthetic cannabinoids, and have included these drugs in the Schedule I category. The depressive respiratory effect in humans caused by synthetic cannabis inhalation has not been thoroughly investigated in the medical literature. We are the first to report, to our knowledge, two cases of self-reported synthetic cannabis use leading to respiratory depression and necessary intubation.

摘要

近年来,合成大麻在青少年中的吸引力不断增加,目前其使用量在高中高年级学生中达到了30年来的峰值。鉴于这种毒品容易获取,合成大麻的成分很难监测。目前,美国40个州已禁止分发和使用一些已知的合成大麻素,并将这些药物列入一类管制药品。吸入合成大麻对人体产生的呼吸抑制作用在医学文献中尚未得到充分研究。据我们所知,我们是首个报告两例自述使用合成大麻导致呼吸抑制并需要插管的病例。

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